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Titolo:
Diffusion tensor imaging and axonal tracking in the human brainstem
Autore:
Stieltjes, B; Kaufmann, WE; van Zijl, PMC; Fredericksen, K; Pearlson, GD; Solaiyappan, M; Mori, S;
Indirizzi:
Johns Hopkins Univ, Sch Med, Dept Radiol & Radiol Sci, Baltimore, MD 21205USA Johns Hopkins Univ Baltimore MD USA 21205 iol Sci, Baltimore, MD 21205USA Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 Pathol, Baltimore, MD 21205 USA Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 Neurol, Baltimore, MD 21205 USA Johns Hopkins Univ, Sch Med, Dept Psychiat, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 ychiat, Baltimore, MD 21205 USA Johns Hopkins Univ, Sch Med, Kennedy Krieger Inst, F M Kirby Res Ctr FunctBrain Imaging, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA21205 maging, Baltimore, MD 21205 USA Johns Hopkins Univ, Sch Med, Dept Mental Hyg, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 al Hyg, Baltimore, MD 21205 USA
Titolo Testata:
NEUROIMAGE
fascicolo: 3, volume: 14, anno: 2001,
pagine: 723 - 735
SICI:
1053-8119(200109)14:3<723:DTIAAT>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANISOTROPIC WATER DIFFUSION; CHARACTERIZING WHITE-MATTER; MYELIN FIBER ORIENTATION; IN-VIVO VISUALIZATION; WEIGHTED MR-IMAGES; MAGNETIC-RESONANCE; NERVOUS-SYSTEM; PROJECTIONS; PATHWAYS; TISSUES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Mori, S Johns Hopkins Univ, Sch Med, Dept Radiol, 720 Rutland Ave,217 Taylor Bldg,Baltimore, MD 21205 USA Johns Hopkins Univ 720 Rutland Ave,217 Taylor Bldg Baltimore MD USA 21205
Citazione:
B. Stieltjes et al., "Diffusion tensor imaging and axonal tracking in the human brainstem", NEUROIMAGE, 14(3), 2001, pp. 723-735

Abstract

Diffusion tensor MRI was used to demonstrate in vivo anatomical mapping ofbrainstem axonal connections. It was possible to identify the corticospinal tract (CST), medial lemniscus, and the superior, medial, and inferior cerebellar peduncles. In addition, the cerebral peduncle could be subparcellated into component tracts, namely, the frontopontine tract, the CST, and thetemporo-/parieto-/occipitopontine tract. Anatomical landmarks and trackingthresholds were established for each fiber and, using these standards, reproducibility of automated tracking as assessed by intra- and interrater reliability was found to be high (kappa > 0.82). Reconstructed fibers corresponded well to existing anatomical knowledge, validating the tracking. Information on the location of individual tracts was coregistered with quantitative MRI maps to automatically measure MRI parameters on a tract-by-tract basis. The results reveal that each tract has a unique spatial signature in terms of water relaxation and diffusion anisotropy. (C) 2001 Academic Press.

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Documento generato il 26/01/20 alle ore 23:00:21