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Titolo:
A prospective comparison of echocardiographic wall motion score index and radionuclide ejection fraction in predicting outcome following acute myocardial infarction
Autore:
Galasko, GIW; Basu, S; Lahiri, A; Senior, R;
Indirizzi:
Northwick Pk Hosp & Clin Res Ctr, Dept Cardiovasc Med, Harrow HA1 3UJ, Middx, England Northwick Pk Hosp & Clin Res Ctr Harrow Middx England HA1 3UJ dx, England
Titolo Testata:
HEART
fascicolo: 3, volume: 86, anno: 2001,
pagine: 271 - 276
SICI:
1355-6037(200109)86:3<271:APCOEW>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR DYSFUNCTION; CLINICAL CHARACTERISTICS; PROGNOSTIC-SIGNIFICANCE; THROMBOLYTIC THERAPY; MORTALITY; TRIAL; REPRODUCIBILITY; TRANDOLAPRIL; ANGIOGRAPHY; SURVIVORS;
Keywords:
echocardiographic wall motion score index; radionuclide ventriculography; prognosis; acute myocardial infarction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Senior, R Northwick Pk Hosp & Clin Res Ctr, Dept Cardiovasc Med, Watford Rd, Harrow HA1 3UJ, Middx, England Northwick Pk Hosp & Clin Res Ctr Watford Rd Harrow Middx England HA1 3UJ
Citazione:
G.I.W. Galasko et al., "A prospective comparison of echocardiographic wall motion score index and radionuclide ejection fraction in predicting outcome following acute myocardial infarction", HEART, 86(3), 2001, pp. 271-276

Abstract

Objective-To characterise echocardiographic wall motion score index (WMSI)as a surrogate measure of left ventricular ejection fraction (EF) following acute myocardial infarction (AMI) and to compare its prognostic value with that of EF measured by radionuclide ventriculography (RNV). Design-A prospective study to compare baseline echocardiographic WMSI withRNV EF in consecutive patients thrombolysed for AMI, both performed on thesame day before discharge, and their relative prognostic values in predicting cardiac events. Setting-District general hospital coronary care unit and cardiology department. Patients-120 consecutive patients free of exclusion criteria thrombolysed for AMI and followed up for a mean (SD) of 13 (10) months. Interventions-None. Main outcome measures-Correlation coefficients and receiver operating characteristic curve analyses plus cardiac event rates at follow up between RNVEF and echocardiographic WMSL. Results-WMSI correlated well with RNV EF. The best corresponding WMSIs forEFs 45%, 40%, and 35% were 0.6, 0.8, and 1.1, respectively. There were 42 cardiac events during follow up. Although both RNV EF and WMSI were strong univariate predictors of cardiac events, only WMSI independently predicted outcome in a multivariate model. All three WMSI cut offs significantly predicted events, while an RNV EF cut off of less than or equal to 45% upsilon > 45% failed to reach significance. Conclusions-Although both RNV and echocardiographic WMSI strongly predicted cardiac outcome, WMSI, a cheaper and more readily available technique, ismore discriminatory, especially in cases of mild left ventricular dysfunction following AMI.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 10:30:41