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Titolo:
Time trends in incidence, mortality, and case-fatality after first episodeof status epilepticus
Autore:
Logroscino, G; Hesdorffer, DC; Cascino, G; Annegers, JF; Hauser, WA;
Indirizzi:
GH Sergievsky Ctr, New York, NY 10032 USA GH Sergievsky Ctr New York NY USA 10032 evsky Ctr, New York, NY 10032 USA Columbia Univ, Dept Neurol, Div Epidemiol, New York, NY USA Columbia UnivNew York NY USA pt Neurol, Div Epidemiol, New York, NY USA Columbia Univ, Sch Publ Hlth, New York, NY USA Columbia Univ New York NY USA mbia Univ, Sch Publ Hlth, New York, NY USA Osped Miulli Acquaviva, Div Neurol, Bari, Italy Osped Miulli Acquaviva Bari Italy li Acquaviva, Div Neurol, Bari, Italy Mayo Clin & Mayo Fdn, Dept Neurol, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn Rochester MN USA 55905 urol, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn, Dept Hlth Sci Res, Rochester, MN 55905 USA Mayo Clin& Mayo Fdn Rochester MN USA 55905 Res, Rochester, MN 55905 USA Univ Texas, Sch Publ Hlth, Houston, TX USA Univ Texas Houston TX USAUniv Texas, Sch Publ Hlth, Houston, TX USA
Titolo Testata:
EPILEPSIA
fascicolo: 8, volume: 42, anno: 2001,
pagine: 1031 - 1035
SICI:
0013-9580(200108)42:8<1031:TTIIMA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ROCHESTER; MINNESOTA; SEIZURES;
Keywords:
status epilepticus; mortality; prognosis; incidence; case fatality;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Hauser, WA GH Sergievsky Ctr, 630 W 168th St, New York, NY 10032 USA GH Sergievsky Ctr 630 W 168th St New York NY USA 10032 0032 USA
Citazione:
G. Logroscino et al., "Time trends in incidence, mortality, and case-fatality after first episodeof status epilepticus", EPILEPSIA, 42(8), 2001, pp. 1031-1035

Abstract

Purpose: Status epilepticus (SE) is a medical emergency associated with a high mortality. Clinical series have suggested that mortality after SE has decreased. No studies have systematically examined trends in incidence, mortality, and case fatality after SE in a well-defined population. Methods: All First episodes of SE receiving medical attention between January 1, 1935, and December 31, 1984, were ascertained through the Rochester Epidemiology Project Records-Linkage System and followed up until death or study termination (February 1, 1996). We calculated incidence rates in the 50-year period (1935-1984), while we considered mortality and case-fatalityin the last 30-year period (1955-1984). Results: Incidence of SE increased over time to 18.1/100,000 (1975 through1984). The increase was related to an increased incidence in the elderly and to the advent of myoclonic SE after cardiac arrest, a condition not seenin the early decades. In the last decade, similar to 16% of the incidence was due to myoclonic SE. The mortality rates increased from 3.6 per year inthe decade 1955-1965 to 4.0/100,000 per year between 1975 and 1984. The 30-day case-fatality (CF) was unchanged, although a trend toward improvement was shown after excluding myoclonic SE. Conclusions: Incidence and mortality rates of SE have increased in the last 30 years. Case fatality remained the same. The increased incidence and mortality are due to the occurrence in the last decade of myoclonic SE after cardiac arrest. The mortality in the elderly was twice that of the youngestage group, across all study periods. Changes in the age and cause distribution of SE over time are responsible for the stable survivorship. There is improvement in survivorship in the last decade when myoclonic SE is excluded.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 13:40:40