Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Recent developments in Rett syndrome research
Autore:
Kerr, AM;
Indirizzi:
Univ Glasgow, Gartnavel Royal Hosp, Monitoring Unit, Acad Ctr,Dept PsycholMed, Glasgow G12 0XH, Lanark, Scotland Univ Glasgow Glasgow Lanark Scotland G12 0XH ow G12 0XH, Lanark, Scotland
Titolo Testata:
CURRENT OPINION IN PSYCHIATRY
fascicolo: 5, volume: 14, anno: 2001,
pagine: 437 - 442
SICI:
0951-7367(200109)14:5<437:RDIRSR>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
LINKED MENTAL-RETARDATION; CPG-BINDING PROTEIN-2; MECP2 GENE; TRANSCRIPTIONAL REPRESSOR; SYNDROME MUTATIONS; MALES; ASSOCIATION; CHROMATIN; DISORDERS; CRITERIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Kerr, AM Univ Glasgow, Gartnavel Royal Hosp, Monitoring Unit, Acad Ctr,Dept PsycholMed, 1055 Great Western Rd, Glasgow G12 0XH, Lanark, Scotland UnivGlasgow 1055 Great Western Rd Glasgow Lanark Scotland G12 0XH
Citazione:
A.M. Kerr, "Recent developments in Rett syndrome research", CUR OPIN P, 14(5), 2001, pp. 437-442

Abstract

Rett syndrome is the familiar expression of a profoundly disabling disorder that follows mutation in the MECP2 gene (chromosome Xq28). Previously recognized only in females, it is clear that males may survive and that the range of severity is wider than was originally appreciated, from mild learning disability to lethal neonatal encephalopathy. Anatomical, neurochemical and physiological studies indicate early failure of neuronal connectivity, specifically involving the brain stem and cerebral cortex, and provide freshinsight into normal and abnormal development. The emergence of a mouse model has improved the prospects for effective intervention. (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/05/20 alle ore 15:40:31