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Titolo:
Regulation of ROMK trafficking and channel activity
Autore:
Huang, CL;
Indirizzi:
Univ Texas, SW Med Ctr, Dept Med, Div Nephrol, Dallas, TX 75390 USA Univ Texas Dallas TX USA 75390 ept Med, Div Nephrol, Dallas, TX 75390 USA
Titolo Testata:
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
fascicolo: 5, volume: 10, anno: 2001,
pagine: 693 - 698
SICI:
1062-4821(200109)10:5<693:RORTAC>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
K-ATP CHANNELS; RECTIFIER POTASSIUM CHANNELS; PLECKSTRIN HOMOLOGY DOMAINS; CORTICAL COLLECTING TUBULE; PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE; FUNCTIONAL EXPRESSION; INTRACELLULAR PH; BETA-GAMMA; DIETARY-K; APICAL-K;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Huang, CL Univ Texas, SW Med Ctr, Dept Med, Div Nephrol, H5-112,Harry Hines Blvd, Dallas, TX 75390 USA Univ Texas H5-112,Harry Hines Blvd Dallas TX USA 75390 75390 USA
Citazione:
C.L. Huang, "Regulation of ROMK trafficking and channel activity", CURR OP NEP, 10(5), 2001, pp. 693-698

Abstract

ROMK potassium channels are present in the thick ascending limbs and cortical collecting ducts of the kidney and are responsible for potassium ion efflux in these segments. ROMK channels are regulated by multiple signalling pathways. This review focuses on recent advances in the regulation of ROMK channels by phosphatidylinositol-4,5-bisphosphate and by membrane trafficking. Relevant publications on the related inward rectifier potassium channels will also be discussed. Curr Opin Nephrol Hypertens 10:693-698. (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 05:52:17