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Titolo:
Electrophysiologic studies in critical illness associated weakness: myopathy or neuropathy - a reappraisal
Autore:
Trojaborg, W; Weimer, LH; Hays, AP;
Indirizzi:
Columbia Univ Coll Phys & Surg, Dept Neurol, New York, NY 10032 USA Columbia Univ Coll Phys & Surg New York NY USA 10032 w York, NY 10032 USA Columbia Univ Coll Phys & Surg, Dept Neuropathol, New York, NY 10032 USA Columbia Univ Coll Phys & Surg New York NY USA 10032 w York, NY 10032 USA
Titolo Testata:
CLINICAL NEUROPHYSIOLOGY
fascicolo: 9, volume: 112, anno: 2001,
pagine: 1586 - 1593
SICI:
1388-2457(200109)112:9<1586:ESICIA>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE QUADRIPLEGIC MYOPATHY; ACUTE CORTICOSTEROID MYOPATHY; MULTIPLE ORGAN FAILURE; INTENSIVE-CARE UNIT; ILL PATIENTS; NEUROMUSCULAR DISORDERS; STATUS-ASTHMATICUS; PROLONGED PARALYSIS; BLOCKING-AGENTS; MOTOR UNITS;
Keywords:
critical illness myopathy; direct muscle stimulation; quantitative EMG; motor unit number estimate;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
64
Recensione:
Indirizzi per estratti:
Indirizzo: Trojaborg, W Helleruplund Alle 3, DK-2900 Hellerup, Denmark Helleruplund Alle 3 Hellerup Denmark DK-2900 lerup, Denmark
Citazione:
W. Trojaborg et al., "Electrophysiologic studies in critical illness associated weakness: myopathy or neuropathy - a reappraisal", CLIN NEU, 112(9), 2001, pp. 1586-1593

Abstract

Objective: Unexplained weakness in critically ill patients is recognized with increasing frequency. However, it is debated whether the condition is aperipheral neuropathy or a myopathy. Diagnostic difficulties can arise from multiple sources that are not generally a factor in other neuromuscular conditions. Conventional electrodiagnostic techniques may provide only non-specific data, clinical examination is often hampered, and muscle biopsy is not a practical screening tool. Method: To improve diagnostic yield, we studied 22 consecutive patients with critical illness associated weakness with additional electrodiagnostic techniques, including direct muscle stimulation, quantitative electromyography, and motor unit number estimation. Results: The applied techniques supported an underlying myopathy in all the patients examined. The diagnosis was confirmed by muscle biopsy in 9 patients. Additional lesser features of neuropathy were concomitantly present in one patient who also underwent sural nerve biopsy. Conclusions: The study suggests that myopathy is much more common than polyneuropathy in critical illness. Suspicion of this entity should be high inthis setting even without exposure to corticosteroids or non-depolarizing blocking agents. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 15:49:36