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Titolo:
Clinical features of atopic dermatitis at two years of age: A prospective,population-based case-control study
Autore:
Bohme, M; Svensson, A; Kull, I; Nordvall, SL; Wahlgren, CF;
Indirizzi:
Karolinska Hosp & Inst, Dept Dermatol, Stockholm, Sweden Karolinska Hosp &Inst Stockholm Sweden ept Dermatol, Stockholm, Sweden Karolinska Hosp & Inst, Dept Venereol, Stockholm, Sweden Karolinska Hosp &Inst Stockholm Sweden ept Venereol, Stockholm, Sweden Univ Hosp MAS, Malmo, Sweden Univ Hosp MAS Malmo SwedenUniv Hosp MAS, Malmo, Sweden Stockholm Cty Council, Dept Environm Hlth, S-10726 Stockholm, Sweden Stockholm Cty Council Stockholm Sweden S-10726 S-10726 Stockholm, Sweden Karolinska Inst, Inst Environm Med, Stockholm, Sweden Karolinska Inst Stockholm Sweden , Inst Environm Med, Stockholm, Sweden Uppsala Univ, Dept Womens & Childrens Hlth, Uppsala, Sweden Uppsala Univ Uppsala Sweden pt Womens & Childrens Hlth, Uppsala, Sweden
Titolo Testata:
ACTA DERMATO-VENEREOLOGICA
fascicolo: 3, volume: 81, anno: 2001,
pagine: 193 - 197
SICI:
0001-5555(200106/07)81:3<193:CFOADA>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
ECZEMA; CHILDREN; PREVALENCE; CRITERIA; RAJKA;
Keywords:
childhood; onset of eczema; atopic sensitization; severity; asthma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Bohme, M Karolinska Hosp & Inst, Dept Dermatol, Stockholm, Sweden Karolinska Hosp & Inst Stockholm Sweden tol, Stockholm, Sweden
Citazione:
M. Bohme et al., "Clinical features of atopic dermatitis at two years of age: A prospective,population-based case-control study", ACT DER-VEN, 81(3), 2001, pp. 193-197

Abstract

While atopic dermatitis (AD) usually presents early in life, few prospective studies focus on young children with AD. The objective of this study wasto characterize, phenotypically and prospectively, young children with AD. From a community birth cohort of 2,256 children, consecutive children withAD (n=221) were followed to 2 years of age, when they were re-examined andscreened for atopic sensitization (skin-prick test to foods; Phadiatop (R)). Ninety-nine controls were also examined. AD debuted during the first year in 88% of cases. At the 2-year examination, when the children had alreadyundergone topical treatment, 157/221 (71%) had ongoing eczema ranging among mild (45%), moderate (53%) and severe (2%). Airway problems indicating asthma had occurred in TA of cases and 6% of controls (not significant), and allergic rhinoconjunctivitis in 5% and 0%, respectively (p <0.05). The skin-prick test to common food allergens was positive in 27% of cases and Phadiatop was positive in 15%. In 67% both tests were negative. Eczema severity did not differ between sensitized and non-sensitized children. Positive Phadiatop was more common in boys than in girls with ongoing AD (22% vs 3%, p <0.01), and more boys than girls had ongoing AD (82% vs 59%, p <0.001); otherwise, no differences attributable to gender were found.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 16:57:58