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Titolo:
Fetal heart rate and umbilical artery velocity variability in fetuses withcongenital cardiac defects: a preliminary study
Autore:
Ursem, NTC; Clark, EB; Pagotto, LT; Wladimiroff, JW;
Indirizzi:
Erasmus Univ, Acad Hosp Rotterdam Dijkzigt, Dept Obstet & Gynaecol, NL-3015 GD Rotterdam, Netherlands Erasmus Univ Rotterdam Netherlands NL-3015 GD GD Rotterdam, Netherlands Univ Utah, Sch Med, Primary Childrens Med Ctr, Med Directors Off, Salt Lake City, UT USA Univ Utah Salt Lake City UT USA ed Directors Off, Salt Lake City, UT USA Univ Utah, Sch Med, Primary Childrens Med Ctr, Div Pediat Cardiol, Salt Lake City, UT USA Univ Utah Salt Lake City UT USA v Pediat Cardiol, Salt Lake City, UT USA
Titolo Testata:
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
fascicolo: 2, volume: 18, anno: 2001,
pagine: 135 - 140
SICI:
0960-7692(200108)18:2<135:FHRAUA>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANS-RETINOIC ACID; NEURAL CREST CELLS; DOPPLER VELOCIMETRY; CHICK-EMBRYOS; WAVE-FORMS; PREGNANCY; GESTATION; APOPTOSIS;
Keywords:
blood flow; congenital defects; fetus; heart rate variability; ultrasound;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Ursem, NTC Erasmus Univ, Acad Hosp Rotterdam Dijkzigt, Dept Obstet & Gynaecol, Dr Molewaterpl 40, NL-3015 GD Rotterdam, Netherlands Erasmus Univ Dr Molewaterpl 40 Rotterdam Netherlands NL-3015 GD
Citazione:
N.T.C. Ursem et al., "Fetal heart rate and umbilical artery velocity variability in fetuses withcongenital cardiac defects: a preliminary study", ULTRASOUN O, 18(2), 2001, pp. 135-140

Abstract

Objective To examine whether variabilities in fetal heart rate and umbilical artery flow velocity are possible markers for hemodynamic dysfunction infetuses with a congenital heart defect. Methods Doppler studies of the umbilical artery velocity waveform were performed at 20-35 weeks of gestation in 13 patients with a congenital heart defect. We determined absolute and variability values for heart rate and flow velocities from umbilical artery velocity, waveforms of a least 18 s duration. We compared these findings with normal controls matched for gestational age. Results Fetuses with a congenital heart defect displayed decreased umbilical artery peak systolic and time-averaged velocities. However, variability in peak systolic and time-averaged velocities and fetal heart rate variability were increased compared with normal controls. Absolute fetal heart rates were similar between the two groups. Conclusions Marked cardiovascular changes occur in the fetus with a congenital heart defect compared with, the normal healthy fetus. We propose that variability in fetal heart rate and umbilical artery blood flow velocity could be additional markers for impaired homeostasis in the presence of fetalcongenital heart disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 00:24:23