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Titolo:
PPAR gamma and inflammatory bowel disease: a new therapeutic target for ulcerative colitis and Crohn's disease
Autore:
Wada, K; Nakajima, A; Blumberg, RS;
Indirizzi:
Osaka Univ, Sch Dent, Dept Pharmacol, Osaka, Japan Osaka Univ Osaka Japan aka Univ, Sch Dent, Dept Pharmacol, Osaka, Japan Yokohama City Univ Sch, Dept Internal Med 3, Yokohama, Kanagawa, Japan Yokohama City Univ Sch Yokohama Kanagawa Japan Yokohama, Kanagawa, Japan Brigham & Womens Hosp, Div Gastroenterol, Boston, MA 02115 USA Brigham & Womens Hosp Boston MA USA 02115 roenterol, Boston, MA 02115 USA Harvard Univ, Sch Med, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 vard Univ, Sch Med, Boston, MA 02115 USA
Titolo Testata:
TRENDS IN MOLECULAR MEDICINE
fascicolo: 8, volume: 7, anno: 2001,
pagine: 329 - 331
SICI:
1471-4914(200108)7:8<329:PGAIBD>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
NF-KAPPA-B; PROLIFERATOR-ACTIVATED RECEPTORS; PHOSPHORYLATION; INHIBIT; LIGANDS;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Wada, K Osaka Univ, Sch Dent, Dept Pharmacol, Osaka, Japan Osaka Univ Osaka Japan , Sch Dent, Dept Pharmacol, Osaka, Japan
Citazione:
K. Wada et al., "PPAR gamma and inflammatory bowel disease: a new therapeutic target for ulcerative colitis and Crohn's disease", TRENDS MO M, 7(8), 2001, pp. 329-331

Abstract

Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclearreceptor that is known to play a central role in adipocyte differentiationand insulin sensitivity. Through work in several animal models of intestinal inflammation, it is now recognized that PPAR gamma also inhibits tissue injury associated with immune activation. These studies point to PPAR gammaas a novel anti-inflammatory mediator with broad therapeutic potential.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 07:59:47