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Titolo:
Yellow fever vector live-virus vaccines: West Nile virus vaccine development
Autore:
Arroyo, J; Miller, CA; Catalan, J; Monath, TP;
Indirizzi:
Acambis Inc, Cambridge, MA 02319 USA Acambis Inc Cambridge MA USA 02319Acambis Inc, Cambridge, MA 02319 USA
Titolo Testata:
TRENDS IN MOLECULAR MEDICINE
fascicolo: 8, volume: 7, anno: 2001,
pagine: 350 - 354
SICI:
1471-4914(200108)7:8<350:YFVLVW>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
JAPANESE ENCEPHALITIS-VIRUS; GENETIC STABILITY; NONHUMAN-PRIMATES; RECOMBINANT; MEASLES; IMMUNOGENICITY; CONSTRUCTION; IMMUNIZATION; MUMPS; CELLS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Arroyo, J Acambis Inc, 38 Sidney St, Cambridge, MA 02319 USA Acambis Inc 38 Sidney St Cambridge MA USA 02319 ge, MA 02319 USA
Citazione:
J. Arroyo et al., "Yellow fever vector live-virus vaccines: West Nile virus vaccine development", TRENDS MO M, 7(8), 2001, pp. 350-354

Abstract

By combining molecular-biological techniques with our increased understanding of the effect of gene sequence modification on viral function, yellow fever 17D, a positive-strand RNA virus vaccine, has been manipulated to induce a protective immune response against viruses of the same family (e.g. Japanese encephalitis and dengue viruses). Triggered by the emergence of WestNile virus infections in the New World afflicting humans, horses and birds, the success of this recombinant technology has prompted the rapid development of a live-virus attenuated candidate vaccine against West Nile virus.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 01:02:38