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Titolo:
The many shapes of mitochondrial membranes
Autore:
Griparic, L; van der Bliek, AM;
Indirizzi:
Univ Calif Los Angeles, Dept Biol Chem, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles, CA 90095 USA
Titolo Testata:
TRAFFIC
fascicolo: 4, volume: 2, anno: 2001,
pagine: 235 - 244
SICI:
1398-9219(200104)2:4<235:TMSOMM>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
DYNAMIN-RELATED GTPASE; DOMINANT OPTIC ATROPHY; BACTERIAL-CELL DIVISION; OUTER-MEMBRANE; CYANIDIOSCHYZON-MEROLAE; INTERMITOCHONDRIAL JUNCTIONS; SACCHAROMYCES-CEREVISIAE; ACTIN CYTOSKELETON; LIVER-MITOCHONDRIA; YEAST REQUIRES;
Keywords:
drp1; dynamin; fuzzy onions; mgm1; mitochondrial cristae; mitochondrial division; mitochondrial fusion;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
100
Recensione:
Indirizzi per estratti:
Indirizzo: van der Bliek, AM Univ Calif Los Angeles, Dept Biol Chem, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 095 USA
Citazione:
L. Griparic e A.M. van der Bliek, "The many shapes of mitochondrial membranes", TRAFFIC, 2(4), 2001, pp. 235-244

Abstract

The roles of mitochondria in cell death and in aging have generated much excitement in recent years. At the same time, however, a quiet revolution inour thinking about mitochondrial ultrastructure has begun. This revolutionstarted with the use of vital dyes and of green fluorescent protein fusionproteins, showing that mitochondria are very dynamic structures that constantly move, divide and fuse throughout the life of a cell. More recently, some of the first proteins contributing to these various processes have beendiscovered. Our view of the internal structures of mitochondria has also changed. Three-dimensional reconstructions obtained with high voltage electron microscopy show that cristae are often connected to the mitochondrial inner membrane by thin tubules. These new insights are brought to bear on thewealth of data collected by conventional electron microscopic analysis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:06:51