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Titolo:
Synthesis and properties of F-18-labeled potential myocardial blood flow tracers
Autore:
Studenov, AR; Berridge, MS;
Indirizzi:
Case Western Reserve Univ, Dept Chem, Cleveland, OH 44106 USA Case WesternReserve Univ Cleveland OH USA 44106 Cleveland, OH 44106 USA Case Western Reserve Univ, Dept Radiol, Cleveland, OH 44106 USA Case Western Reserve Univ Cleveland OH USA 44106 Cleveland, OH 44106 USA Univ Hosp Cleveland, Cleveland, OH 44106 USA Univ Hosp Cleveland Cleveland OH USA 44106 eland, Cleveland, OH 44106 USA
Titolo Testata:
NUCLEAR MEDICINE AND BIOLOGY
fascicolo: 6, volume: 28, anno: 2001,
pagine: 683 - 693
SICI:
0969-8051(200108)28:6<683:SAPOFP>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
PET; ACETYLCHOLINESTERASE; BIODISTRIBUTION; COMPLEXES; LIGANDS;
Keywords:
fluorine-18; perfusion heart; myocardium; acetylcholinesterase;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Studenov, AR Case Western Reserve Univ, Dept Chem, Cleveland, OH 44106 USACase Western Reserve Univ Cleveland OH USA 44106 H 44106 USA
Citazione:
A.R. Studenov e M.S. Berridge, "Synthesis and properties of F-18-labeled potential myocardial blood flow tracers", NUCL MED BI, 28(6), 2001, pp. 683-693

Abstract

PET centers without particle accelerators make clinical PET widely available at reduced cost. For myocardial perfusion tracers, these satellite PET centers are limited to generator- produced Rb-82(+) and Cu-62[PTSM]. Their limitations motivate a search for transportable alternatives. In search of new tracers we have synthesized several F-18-labeled amines and quaternary ammonium salts. Among them, 4-[F-18]fluorotri-N-methylanilinium ([F-18]FTMA)has flow-tracing proper-ties. The compound is functional, but has properties that justify a continued search. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 08:21:41