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Titolo:
The effect of tryptophan on social interaction in everyday life: A placebo-controlled study
Autore:
Moskowitz, DS; Pinard, G; Zuroff, DC; Annable, L; Young, SN;
Indirizzi:
McGill Univ, Dept Psychol, Montreal, PQ H3A 1B1, Canada McGill Univ Montreal PQ Canada H3A 1B1 chol, Montreal, PQ H3A 1B1, Canada McGill Univ, Dept Psychiat, Montreal, PQ H3A 2T5, Canada McGill Univ Montreal PQ Canada H3A 2T5 hiat, Montreal, PQ H3A 2T5, Canada
Titolo Testata:
NEUROPSYCHOPHARMACOLOGY
fascicolo: 2, volume: 25, anno: 2001,
pagine: 277 - 289
SICI:
0893-133X(200108)25:2<277:TEOTOS>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
CERCOPITHECUS-AETHIOPS-SABAEUS; VERVET MONKEYS; 5-HYDROXYINDOLEACETIC ACID; DOMINANCE ACQUISITION; AGGRESSIVE-BEHAVIOR; CEREBROSPINAL-FLUID; NONHUMAN-PRIMATES; ORAL TRYPTOPHAN; SEROTONIN; BRAIN;
Keywords:
social behavior; dominance-subordination; affect; arousal; tryptophan; serotonin;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
64
Recensione:
Indirizzi per estratti:
Indirizzo: Moskowitz, DS McGill Univ, Dept Psychol, 1205 Dr Penfield Ave, Montreal, PQ H3A 1B1, Canada McGill Univ 1205 Dr Penfield Ave Montreal PQ Canada H3A 1B1
Citazione:
D.S. Moskowitz et al., "The effect of tryptophan on social interaction in everyday life: A placebo-controlled study", NEUROPSYCH, 25(2), 2001, pp. 277-289

Abstract

In monkeys increasing serotonin function enhances affiliative interactionsand promotes the acquisition of dominance. To examine whether similar effects occur in humans, we treated 98 subjects for 12 days with the serotonin precursor tryptophan (1g TID) and for 12 days with placebo in a double-blind, cross over study. Agreeableness/quarrelsomeness and dominance/submissionwere measured using an event-contingent method, in which subjects reportedon various behaviors during important social interactions throughout theirday. Tryptophan decreased quarrelsome behavior, but only when placebo was given first, suggesting that a decrease in quarrelsomeness when tryptophan was given first may have carried over into the subsequent placebo period. Tryptophan increased dominant behavior, an effect that was independent of the order of treatment, the broad social context, and the subject's and partner's sex. Our results suggest that serotonin may enhance dominance in humans, as in monkeys, and illustrate the advantages of the event contingent methodology in studying the associations between biology and human social interaction. [Neuropsychopharmacology 25:277-289,2001] (C) 2001 American College of Neuropsychopharmacology. Published by Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 21:02:49