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Titolo:
Optimal therapy of pubertal disorders in precocious/early puberty
Autore:
Tato, L; Savage, MO; Antoniazzi, F; Buzi, F; Di Maio, S; Oostdijk, W; Pasquino, AM; Raiola, G; Saenger, P; Tonini, G; Voorhoeve, PG;
Indirizzi:
Univ Verona, Policlin Giambattista Rossi, Pediat Clin, I-37134 Verona, Italy Univ Verona Verona Italy I-37134 ssi, Pediat Clin, I-37134 Verona, Italy St Bartholomews Hosp, Dept Pediat Endocrinol, London, England St Bartholomews Hosp London England Pediat Endocrinol, London, England Univ Brescia, Ctr Growth & Endocrinol, Brescia, Italy Univ Brescia Brescia Italy cia, Ctr Growth & Endocrinol, Brescia, Italy Univ Naples Federico II, Dept Paediat, Naples, Italy Univ Naples Federico II Naples Italy co II, Dept Paediat, Naples, Italy Leiden Univ Hosp, Dept Paediat, Leiden, Netherlands Leiden Univ Hosp Leiden Netherlands , Dept Paediat, Leiden, Netherlands Univ Roma La Sapienza, Paediat Endocrinol Serv, Rome, Italy Univ Roma La Sapienza Rome Italy , Paediat Endocrinol Serv, Rome, Italy Ospet AO Pugliese Ciaccio, Dept Paediat, Catanzaro, Italy Ospet AO Pugliese Ciaccio Catanzaro Italy ept Paediat, Catanzaro, Italy Albert Einstein Coll Med, Montefiore Med Ctr, Div Pediat Endocrinol, New York, NY USA Albert Einstein Coll Med New York NY USA at Endocrinol, New York, NY USA Childrens Hosp Burlo Garofolo, Paediat Endocrinol Auxol Unit, Trieste, Italy Childrens Hosp Burlo Garofolo Trieste Italy Auxol Unit, Trieste, Italy Free Univ Amsterdam Hosp, Dept Paediat Endocrinol, Amsterdam, Netherlands Free Univ Amsterdam Hosp Amsterdam Netherlands , Amsterdam, Netherlands
Titolo Testata:
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
, volume: 14, anno: 2001, supplemento:, 2
pagine: 985 - 995
SICI:
0334-018X(200107)14:<985:OTOPDI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
HORMONE AGONIST TREATMENT; ISOLATED PREMATURE THELARCHE; RECOMBINANT CELL BIOASSAY; GROWTH-FACTOR-ALPHA; TERM FOLLOW-UP; BONE-MINERAL DENSITY; FINAL HEIGHT; LUTEINIZING-HORMONE; SEXUAL PRECOCITY; ANALOG TREATMENT;
Keywords:
puberty; pubertal disorders; precocious puberty; early puberty; therapy for pubertal disorders; consensus guidelines;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
76
Recensione:
Indirizzi per estratti:
Indirizzo: Tato, L Univ Verona, Policlin Giambattista Rossi, Pediat Clin, Piazza Ludovico Antonio Scuro 10, I-37134 Verona, Italy Univ Verona Piazza Ludovico Antonio Scuro 10 Verona Italy I-37134
Citazione:
L. Tato et al., "Optimal therapy of pubertal disorders in precocious/early puberty", J PED END M, 14, 2001, pp. 985-995

Abstract

GnRHa have been used in the treatment of central precocious puberty (CPP) for a decade and some final results of this therapy are now available. Treatment preserves height potential in younger patients and a complete recovery of the hypothalamic-pituitary-gonadal axis occurs at the end of treatment. However, some aspects of the management of CPP are still debated. Probably the age limits between normal and precocious puberty have to be lowered, and new diagnostic tools will modify and simplify diagnostic criteria. The possibility of progression of premature thelarche into precocious puberty, the pathogenesis of organic and idiopathic precocious puberty, the criteriafor decision to treat and to stop treatment and the utility of an association with GH treatment will be better understood in the future. Follow-up ofpatients after stopping therapy includes frequency and characteristics of menses, the possible higher incidence of polycystic ovary-like syndrome andthe correct achievement of a normal peak bone mass and body composition. In this review we discuss some of these points, with particular attention toprecocious puberty in girls.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 06:48:43