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Titolo:
The salivary adenosine/AMP content of Phlebotomus argentipes Annandale andBrunetti, the main vector of human kala-azar
Autore:
Ribeiro, JMC; Modi, G;
Indirizzi:
Parasit Dis Lab, Sect Med Entomol, Bethesda, MD 20892 USA Parasit Dis LabBethesda MD USA 20892 Med Entomol, Bethesda, MD 20892 USA
Titolo Testata:
JOURNAL OF PARASITOLOGY
fascicolo: 4, volume: 87, anno: 2001,
pagine: 915 - 917
SICI:
0022-3395(200108)87:4<915:TSACOP>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
SAND FLY SALIVA; LUTZOMYIA-LONGIPALPIS; TNF-ALPHA; RECEPTOR; LEISHMANIASIS; MACROPHAGES; INFECTION; MAXADILAN; PEPTIDE; MICE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Ribeiro, JMC Parasit Dis Lab, Sect Med Entomol, Bldg 4,Rm 126,4 Ctr Dr,MSC0425, Bethesda, MD 20892 USA Parasit Dis Lab Bldg 4,Rm 126,4 Ctr Dr,MSC 0425 Bethesda MD USA 20892
Citazione:
J.M.C. Ribeiro e G. Modi, "The salivary adenosine/AMP content of Phlebotomus argentipes Annandale andBrunetti, the main vector of human kala-azar", J PARASITOL, 87(4), 2001, pp. 915-917

Abstract

Adenosine and AMP in the salivary glands of the sand fly Phlebotomus argentipes were characterized by reversed-phase high-pressure liquid chromatography with diode-array detection and mass spectrometry. AMP and adenosine were measured in individual salivary gland pairs, yielding 76.8 +/- 8.6 and 380 +/- 25 pmoles per pair of salivary glands, respectively (mean +/- SE, n =12). These values decrease to 45 +/- 7 and 181 +/- 21 pmoles following a blood meal, indicating that AMP and adenosine were secreted. Because adenosine and AMP have anti-platelet, vasodilatory, and immunomodulatory properties, it is proposed that these salivary nucleotides help the fly to blood feed and may affect Leishmania transmission.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 00:04:59