Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Supine and exercise systolic blood pressure predict cardiovascular death in middle-aged men
Autore:
Kjeldsen, SE; Mundal, R; Sandvik, L; Erikssen, G; Thaulow, E; Erikssen, J;
Indirizzi:
Univ Oslo, Ullevaal Hosp, Dept Cardiol, N-0407 Oslo, Norway Univ Oslo Oslo Norway N-0407 aal Hosp, Dept Cardiol, N-0407 Oslo, Norway Cent Hosp Akershus, Dept Internal Med, Nordbyhagen, Norway Cent Hosp Akershus Nordbyhagen Norway Internal Med, Nordbyhagen, Norway
Titolo Testata:
JOURNAL OF HYPERTENSION
fascicolo: 8, volume: 19, anno: 2001,
pagine: 1343 - 1348
SICI:
0263-6352(200108)19:8<1343:SAESBP>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLINICAL-PRACTICE; PHYSICAL-FITNESS; HYPERTENSIVE MEN; PROGNOSTIC VALUE; MORTALITY; HEALTHY; SENSITIVITY; REST;
Keywords:
blood pressure; cardiovascular mortality; exercise testing; hypertension; myocardial infarction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Kjeldsen, SE Univ Oslo, Ullevaal Hosp, Dept Cardiol, N-0407 Oslo, Norway Univ Oslo Oslo Norway N-0407 t Cardiol, N-0407 Oslo, Norway
Citazione:
S.E. Kjeldsen et al., "Supine and exercise systolic blood pressure predict cardiovascular death in middle-aged men", J HYPERTENS, 19(8), 2001, pp. 1343-1348

Abstract

Aim and methods The outcome of 1999 apparently healthy men, aged 40-59 years, initially investigated in the period 1972-1975, has previously been ascertained at 7 and 16 year follow-ups. This has now been repeated after 21 years, to determine whether seated systolic blood pressure (BP) during a bicycle ergometer exercise test adds prognostic information on cardiovascular (CV) mortality beyond that of systolic BP measured after 5 min of supine rest. Results After 21 years, 41 979 years of observation, 470 patients had died, 255 from CV causes. Supine systolic BP [2 SD increase: relative risk (RR)1.6, 95% confidence interval (CI) 1.3-2.0, P < 0.0001], 6 min exercise systolic BP (2 SD increase: RR 1.6, 95% CI 1.3-2.0, P < 0.0001) on the starting workload of 600 kpm/min (approximate to 100 W, 5880 J/min) and maximal systolic BP (2 SD increase: RR 1.5, 95% CI 1.2-1.9, P = 0.0005) during work were all related to CV mortality when adjusting for a large number of variables measured in the present study including age, exercise capacity, heart rates, smoking habits, glucose tolerance and serum cholesterol. When including other systolic Bps in the continuous multivariate analysis, supine systolic BP (2 SD increase: RR 1.4, 95% CI 1.04-1.9, P = 0.029) and 6 min systolic BP at 600 kpm/min (2 SD increase: RR 1.4,95% CI 1.06-1.9, P = 0.017) were independent predictors of CV death but not maximal systolic BP during exercise (2 SD increase: RR 1.0, 95% CI 0.7-1.2, P = 0.95). Conclusion These results are different from the mortality data at 16 years, when the independent predictive effect of supine systolic BP was cancelled out by 6 min exercise systolic BP at 600 kpm/min. Twenty-one years of follow-up of 1999 apparently healthy men disclose independently predictive information on CV death, of both supine systolic BP and 6 min exercise systolic BP taken at an early moderate workload. The influence of maximal exercisesystolic BP on CV death is however cancelled out by the two other systolicBps. (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 10:13:01