Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Acute liver failure
Autore:
Gill, RQ; Sterling, RK;
Indirizzi:
Virginia Commonwealth Univ, Coll Med, Sect Hepatol & Liver Transplantat, Div Gastroenterol, Richmond, VA 23298 USA Virginia Commonwealth Univ Richmond VA USA 23298 , Richmond, VA 23298 USA
Titolo Testata:
JOURNAL OF CLINICAL GASTROENTEROLOGY
fascicolo: 3, volume: 33, anno: 2001,
pagine: 191 - 198
SICI:
0192-0790(200109)33:3<191:ALF>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
FULMINANT HEPATIC-FAILURE; COAGULATION-FACTOR-V; CONTROLLED TRIAL; PROGNOSTIC INDICATORS; PARACETAMOL OVERDOSE; CLINICAL-EXPERIENCE; TRANSPLANTATION; ENCEPHALOPATHY; MANAGEMENT; CRITERIA;
Keywords:
acute liver failure; fulminant hepatic failure; therapy;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
62
Recensione:
Indirizzi per estratti:
Indirizzo: Sterling, RK Virginia Commonwealth Univ, Coll Med, Sect Hepatol & Liver Transplantat, Div Gastroenterol,West Hosp, Box 980341,1200 E Broad St,Room 1492, Richmond,VA 23298 USA Virginia Commonwealth Univ Box 980341,1200 E Broad St,Room 1492 Richmond VA USA 23298
Citazione:
R.Q. Gill e R.K. Sterling, "Acute liver failure", J CLIN GAST, 33(3), 2001, pp. 191-198

Abstract

Acute liver failure (ALF) is defined as hepatic encephalopathy complicating acute liver injury. The most common etiologies are acute viral hepatitis A and B, medication overdose (e.g., acetaminophen), idiosyncratic drug reactions, ingestion of other toxins (e.g., amanita mushroom poisoning), and metabolic disorders (e.g., Reye's syndrome). Despite advances in intensive care management, mortality continues to be high (40-80%) and is partly related to ALF's complications, such as cerebral edema, sepsis, hypoglycemia, gastrointestinal bleeding, and acute renal failure. Several prognostic models have been developed to determine which patients will spontaneously recover. Treatment is directed at early recognition of the complications and general supportive measures. The only proven therapy for those who are unlikely to recover is liver transplantation. Therefore, recognition of ALF is paramount, and urgent referral to a transplant center is critical to assess transplantation status.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 06:34:57