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Titolo:
Dose of prophylactic intravenous ephedrine during spinal anesthesia for cesarean section
Autore:
Simon, L; Provenchere, S; Blanquat, LD; Boulay, G; Hamza, J;
Indirizzi:
Hop St Vincent de Paul, Serv Anesthesie Reanimat, F-75014 Paris, France Hop St Vincent de Paul Paris France F-75014 nimat, F-75014 Paris, France
Titolo Testata:
JOURNAL OF CLINICAL ANESTHESIA
fascicolo: 5, volume: 13, anno: 2001,
pagine: 366 - 369
SICI:
0952-8180(200108)13:5<366:DOPIED>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
MATERNAL HYPOTENSION; ANGIOTENSIN-II; PREVENTION; INFUSION; DELIVERY; PHENYLEPHRINE; FENTANYL; PRELOAD;
Keywords:
anesthesia : obstetrical; spinal; ephedrine; hypotension;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Simon, L Hop St Vincent de Paul, Serv Anesthesie Reanimat, 74-82 Ave Denfert Rochereau, F-75014 Paris, France Hop St Vincent de Paul 74-82 Ave Denfert Rochereau Paris France F-75014
Citazione:
L. Simon et al., "Dose of prophylactic intravenous ephedrine during spinal anesthesia for cesarean section", J CLIN ANES, 13(5), 2001, pp. 366-369

Abstract

Study Objective: To compare the incidence of maternal hypotension associated with spinal anesthesia for cesarean section when 10-, 15-, or 20-mg prophylactic boluses of intravenous (TV) ephedrine are used. Design: Prospective observational study. Setting: Teaching hospitalPatients: 108 women admitted for elective cesarean section. Interventions: Spinal anesthesia was performed using hyperbaric bupivacaine 10 mg, sufentanil 2 mug, and morphine 0.2 mg (volume 4 mL). Ephedrine (10, 15, or 20 mg) was administered 2 minutes after the intrathecal injection. Maternal blood pressure was checked every 2 minutes. Hypotension was promptly treated with 5-mg ephedrine boluses. Main Results: Incidence of hypotension was significantly higher in women receiving a 10-mg prophylactic dose of ephedrine than in those receiving either a 15-mg or a 20-mg prophylactic dose of ephedrine [23/36 in the 10-mg ephedrine group vs. 13/36 and 10/36 in the 15-mg and 20-mg ephedrine groups,respectively (p < 0.05)]. Conclusion: In the conditions of this study, a single bolus of I-V ephedrine with doses of either 15 or 20 mg decreased significantly the incidence of maternal hypotension as compared to a single. 10-mg bolus of ephedrine. (C) 2001 by Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 22:25:58