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Titolo:
Transcranial Doppler ultrasonography with induction of anesthesia and neuromuscular blockade in surgical patients
Autore:
Kofke, WA; Shaheen, N; McWhorter, J; Sinz, EH; Hobbs, G;
Indirizzi:
W Virginia Univ, Hlth Sci Ctr, Dept Anesthesiol, Morgantown, WV 26506 USA W Virginia Univ Morgantown WV USA 26506 thesiol, Morgantown, WV 26506 USA
Titolo Testata:
JOURNAL OF CLINICAL ANESTHESIA
fascicolo: 5, volume: 13, anno: 2001,
pagine: 335 - 338
SICI:
0952-8180(200108)13:5<335:TDUWIO>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRACRANIAL-PRESSURE; NEUROSURGICAL PATIENTS; NEUROANESTHESIA; INTUBATION;
Keywords:
brain : blood flow velocity; muscle relaxants : cis-atracurium, rocuronium;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
8
Recensione:
Indirizzi per estratti:
Indirizzo: Kofke, WA Univ Penn, Dept Anesthesia, Sch Med, 7 Dulles,3400 Spruce St, Philadelphia, PA 19104 USA Univ Penn 7 Dulles,3400 Spruce St Philadelphia PA USA 19104 USA
Citazione:
W.A. Kofke et al., "Transcranial Doppler ultrasonography with induction of anesthesia and neuromuscular blockade in surgical patients", J CLIN ANES, 13(5), 2001, pp. 335-338

Abstract

Study Objectives: To evaluate the cerebral vascular effects of cis-atracurium and rocuronium given after thiopental induction of anesthesia. Design: Randomized, single-blinded study. Setting: University-affiliated hospitalPatients: 39 adult ASA physical status I and II patients undergoing nonintracranial procedures. Interventions: Patients received intravenously (TV), either saline placebo, cis-atracurium, or rocuronium after induction of general anesthesia with thiopental sodium. Measurements: The right middle cerebral artery was insonated using a pulsed-wave range-gated transcranial Doppler and data were recorded at preinduction, immediately postinduction, at injection of the study drug, and at 15-second intervals for 3 minutes thereafter. The variables recorded for each subject included the systolic, diastolic, and mean flow velocity, as well aspulsality index, systolic, diastolic, and mean arterial blood pressure (MAP), and end-tidal carbon dioxide concentration. MainResults: No significant differences between the groups were present in thepostanesthetic induction maximal or minimal mean flow velocity. Conclusions: cis-Atracurium and rocuronium, administered after thiopental,do not produce clinically relevant changes in cerebral bloodflow velocity. (C) 2001 by Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 22:37:00