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Titolo:
Neuropsychological effects of prefrontal slow rTMS in normal volunteers: Adouble-blind sham-controlled study
Autore:
Koren, D; Shefer, O; Chistyakov, A; Kaplan, B; Feinsod, M; Klein, E;
Indirizzi:
Rambam Med Ctr, Dept Psychiat, Bruce Rappaport Fac Med, Technion Israel Inst Technol, IL-31096 Haifa, Israel Rambam Med Ctr Haifa Israel IL-31096 nst Technol, IL-31096 Haifa, Israel Univ Haifa, Dept Psychol, IL-31999 Haifa, Israel Univ Haifa Haifa IsraelIL-31999 a, Dept Psychol, IL-31999 Haifa, Israel Technion Israel Inst Technol, Bruce Rappaport Fac Med, Rambam Med Ctr, Dept Neurosurg, IL-31096 Haifa, Israel Technion Israel Inst Technol Haifa Israel IL-31096 L-31096 Haifa, Israel
Titolo Testata:
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY
fascicolo: 4, volume: 23, anno: 2001,
pagine: 424 - 430
SICI:
1380-3395(200108)23:4<424:NEOPSR>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSCRANIAL MAGNETIC STIMULATION; SHORT-TERM-MEMORY; DEPRESSION; CORTEX; SAFETY; INDUCTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Klein, E Rambam Med Ctr, Dept Psychiat, Bruce Rappaport Fac Med, Technion Israel Inst Technol, Efron St, IL-31096 Haifa, Israel Rambam Med Ctr Efron St Haifa Israel IL-31096 1096 Haifa, Israel
Citazione:
D. Koren et al., "Neuropsychological effects of prefrontal slow rTMS in normal volunteers: Adouble-blind sham-controlled study", J CL EXP N, 23(4), 2001, pp. 424-430

Abstract

Recent reports have suggested that repetitive transcranial magnetic stimulation (rTMS) is effective in major depression. Unlike ECT, rTMS does not involve a seizure and is associated with minimal side-effects, including cognitive difficulties. However. the effect of rTMS on cognitive functioning has not been systematically evaluated. This study was designed to examine theneuropsychological effects of slow rTMS in normal volunteers. Forty-six normal volunteers were randomly assigned to receive one session of tight (N=16) or left prefrontal (N=15), or sham (N=15) rTMS at I HZ. Patients were assessed before and after stimulation by a computerized neurospychological battery. All three groups showed significant improvement over time in processing speed (reaction time) and efficiency (correct responses per unit of time). However, no time by group interaction was found for any of the neuropsychological tests. These findings suggest that a single session of slow rTMSdoes not interfere with neurospychological functioning in normal volunteers, supporting clinical reports of no adverse cognitive effects.

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Documento generato il 19/01/20 alle ore 09:23:00