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Titolo:
Low-attenuation areas of the lungs on high-resolution computed tomography in asthma
Autore:
Mitsunobu, F; Mifune, T; Ashida, K; Hosaki, Y; Tsugeno, H; Okamoto, M; Harada, S; Tanizaki, Y;
Indirizzi:
Okayama Univ, Sch Med, Dept Med, Misasa Med Branch, Tottori 6820192, JapanOkayama Univ Tottori Japan 6820192 sa Med Branch, Tottori 6820192, Japan
Titolo Testata:
JOURNAL OF ASTHMA
fascicolo: 5, volume: 38, anno: 2001,
pagine: 413 - 422
SICI:
0277-0903(2001)38:5<413:LAOTLO>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
PULMONARY-EMPHYSEMA; CHEST RADIOGRAPHY; BRONCHIAL-ASTHMA; DISEASE SEVERITY; DENSITY; CT; DIAGNOSIS; HYPERINFLATION; MORPHOMETRY; AIRWAYS;
Keywords:
asthma; DLCO; FEV1; high-resolution computed tomography; low-attenuation area;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Mitsunobu, F Okayama Univ, Sch Med, Dept Med, Misasa Med Branch, 827 Yamada, Tottori 6820192, Japan Okayama Univ 827 Yamada Tottori Japan 6820192 6820192, Japan
Citazione:
F. Mitsunobu et al., "Low-attenuation areas of the lungs on high-resolution computed tomography in asthma", J ASTHMA, 38(5), 2001, pp. 413-422

Abstract

To investigate the low-attenuation areas of the lungs (LAA) in asthma, we compared the mean lung density (MLD) and the LAA in 22 asthmatics (12 ex-smokers and 10 nonsmokers) and 13 patients with chronic obstructive pulmonarydisease (COPD) by high-resolution computed tomography. The MLD and the relative area of the lung with attenuation values lower than -950 Hounsfield Units at full inspiration (inspiratory RA(950)) were significantly differentin nonsmoking asthmatics compared to patients with COPD and asthmatics with a smoking history. The MLD and the RA(950) correlated significantly with the FEV1 in all groups and with the DLCO in patients with COPD and asthmatics with a smoking history but not in nonsmoking asthmatics. We concluded that the LAA in asthmatics with a smoking history indicates the presence of emphysema, but in nonsmoking asthmatics it reflects hyperinflation and nonemphysematous expiratory airflow limitation rather than emphysematous lesions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 21:05:58