Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Evidence of LPL gene-exercise interaction for body fat and LPL activity: the HERITAGE Family Study
Autore:
Garenc, C; Perusse, L; Bergeron, J; Gagnon, J; Chagnon, YC; Borecki, IB; Leon, AS; Skinner, JS; Wilmore, JH; Rao, DC; Bouchard, C;
Indirizzi:
Univ Laval, PEPS, Dept Prevent Med, Div Kinesiol, St Foy, PQ G1K 7P4, Canada Univ Laval St Foy PQ Canada G1K 7P4 Kinesiol, St Foy, PQ G1K 7P4, Canada Univ Laval, Med Res Ctr, Mol Endocrinol Lab, St Foy, PQ G1K 7P4, Canada Univ Laval St Foy PQ Canada G1K 7P4 rinol Lab, St Foy, PQ G1K 7P4, Canada Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA Washington Univ St Louis MO USA 63110 Div Biostat, St Louis, MO 63110 USA Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA Washington Univ St Louis MO USA 63110 Dept Genet, St Louis, MO 63110 USA Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA WashingtonUniv St Louis MO USA 63110 pt Psychiat, St Louis, MO 63110 USA Univ Minnesota, Sch Kinesiol & Leisure Studies, Minneapolis, MN 55454 USA Univ Minnesota Minneapolis MN USA 55454 tudies, Minneapolis, MN 55454 USA Indiana Univ, Dept Kinesiol, Bloomington, IN 47405 USA Indiana Univ Bloomington IN USA 47405 Kinesiol, Bloomington, IN 47405 USA Texas A&M Univ, Dept Hlth & Kinesiol, College Stn, TX 77843 USA Texas A&M Univ College Stn TX USA 77843 nesiol, College Stn, TX 77843 USA Louisiana State Univ, Pennington Biomed Res Ctr, Baton Rouge, LA 70803 USALouisiana State Univ Baton Rouge LA USA 70803 , Baton Rouge, LA 70803 USA
Titolo Testata:
JOURNAL OF APPLIED PHYSIOLOGY
fascicolo: 3, volume: 91, anno: 2001,
pagine: 1334 - 1340
SICI:
8750-7587(200109)91:3<1334:EOLGIF>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIPOPROTEIN-LIPASE GENE; CORONARY-ARTERY DISEASE; ABDOMINAL VISCERAL FAT; ADIPOSE-TISSUE; PLASMA-LIPIDS; CARDIOVASCULAR-DISEASE; PHYSICAL-ACTIVITY; SKELETAL-MUSCLE; WOMEN; RESEMBLANCE;
Keywords:
lipoprotein lipase gene; lipoprotein lipase S447X polymorphism; association; interaction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Perusse, L Univ Laval, PEPS, Dept Prevent Med, Div Kinesiol, St Foy, PQ G1K 7P4, Canada Univ Laval St Foy PQ Canada G1K 7P4 St Foy, PQ G1K 7P4, Canada
Citazione:
C. Garenc et al., "Evidence of LPL gene-exercise interaction for body fat and LPL activity: the HERITAGE Family Study", J APP PHYSL, 91(3), 2001, pp. 1334-1340

Abstract

Evidence of a gene-exercise interaction for traits related to body composition is limited. Here, the association between the lipoprotein lipase (LPL)S447X polymorphism and changes in body mass index, fat mass, percent body fat, abdominal visceral fat measured by computed tomography, and post-heparin plasma LPL activity in response to 20 wk of endurance training was investigated in 741 adult white and black subjects. Changes were compared between carriers and noncarriers of the X447 allele after adjustment for the effects of age and pretraining values. No evidence of association was observed in men. However, white women carrying the X447 allele exhibited greater reductions of body mass index (P = 0.01), fat mass (P = 0.01), and percent body fat (P = 0.03); in black women, the carriers exhibited a greater reduction of abdominal visceral fat (P = 0.05) and a greater increase in post-heparin LPL activity (P = 0.02). These results suggest that the LPL S447X polymorphism influences the training-induced changes in body fat and post-heparinLPL activity in women but not in men.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/12/19 alle ore 15:24:49