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Titolo:
Effects of beacon administration on energy expenditure and substrate utilisation in Psammomys obesus (Israeli sand rats)
Autore:
Walder, K; McMillan, JS; Lee, S; Civitarese, A; Zimmet, P; Collier, GR;
Indirizzi:
Deakin Univ, Sch Hlth Sci, Metab Res Unit, Geelong, Vic 3217, Australia Deakin Univ Geelong Vic Australia 3217 Unit, Geelong, Vic 3217, Australia Int Diabet Inst, Caulfield, Vic, Australia Int Diabet Inst Caulfield Vic Australia Inst, Caulfield, Vic, Australia
Titolo Testata:
INTERNATIONAL JOURNAL OF OBESITY
fascicolo: 9, volume: 25, anno: 2001,
pagine: 1281 - 1285
SICI:
0307-0565(200109)25:9<1281:EOBAOE>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
MELANIN-CONCENTRATING HORMONE; NEUROPEPTIDE-Y; FEEDING-BEHAVIOR; BODY-WEIGHT; MICE; GENE; METABOLISM; NARCOLEPSY; OREXINS; SLEEP;
Keywords:
beacon; Psammomys obesus; calorimetry; physical activity; energy expenditure; adipose tissue;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Walder, K Deakin Univ, Sch Hlth Sci, Metab Res Unit, Geelong, Vic 3217, Australia Deakin Univ Geelong Vic Australia 3217 ong, Vic 3217, Australia
Citazione:
K. Walder et al., "Effects of beacon administration on energy expenditure and substrate utilisation in Psammomys obesus (Israeli sand rats)", INT J OBES, 25(9), 2001, pp. 1281-1285

Abstract

OBJECTIVE: To investigate whether beacon administration affects substrate utilisation, physical activity levels or energy expenditure in Psammomys obesus. DESIGN: Pairs of age- and sex-matched Psammomys obesus were randomly assigned to either beacon-treated (15 mug/day for 7 days (i.c.v.)) or control (i.c.v. saline) groups. MEASUREMENTS: Indirect calorimetry on day 0 and day 7 to measure oxygen consumption and carbon dioxide production, which were used to calculate fat oxidation, carbohydrate oxidation and total energy expenditure. Physical activity in the calorimeter was measured using an infrared beam system. Food intake and body weight were measured daily. RESULTS: The administration of beacon significantly increased body weight compared to saline-treated control animals. This body weight gain was primarily due to increased body fat content. Average daily food intake tended tobe higher in beacon-treated Psammomys obesus, but no effect of beacon administration on substrate oxidation, activity or energy expenditure was detected. CONCLUSION: The effects of beacon on body weight are due to increased foodintake, with no detectable effect on nutrient partitioning, physical activity or energy expenditure.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 20:27:52