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Titolo:
Enhancement of SPECT reconstructions by means of coregistered MR data
Autore:
Calvini, P; Vitali, P; Nobili, F; Rodriguez, G;
Indirizzi:
Univ Genoa, INFM, Dipartimento Fis, I-16146 Genoa, Italy Univ Genoa Genoa Italy I-16146 M, Dipartimento Fis, I-16146 Genoa, Italy Univ Genoa, Dipartimento Med Interna, Serv Neurofisiol, I-16132 Genoa, Italy Univ Genoa Genoa Italy I-16132 a, Serv Neurofisiol, I-16132 Genoa, Italy
Titolo Testata:
IEEE TRANSACTIONS ON NUCLEAR SCIENCE
fascicolo: 3, volume: 48, anno: 2001,
parte:, 2
pagine: 750 - 755
SICI:
0018-9499(200106)48:3<750:EOSRBM>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
EMISSION COMPUTED-TOMOGRAPHY; BAYESIAN RECONSTRUCTION; IMAGE-RECONSTRUCTION; BRAIN; REGISTRATION; ALGORITHM; COMPENSATION; QUANTITATION; INFORMATION; RESOLUTION;
Keywords:
conjugate gradients; functional imaging; iterative reconstruction techniques; multimodality imaging; single photon emission computed tomography (SPECT) quantitation; SPECT reconstruction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Engineering, Computing & Technology
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Calvini, P Univ Genoa, INFM, Dipartimento Fis, I-16146 Genoa, Italy Univ Genoa Genoa Italy I-16146 ento Fis, I-16146 Genoa, Italy
Citazione:
P. Calvini et al., "Enhancement of SPECT reconstructions by means of coregistered MR data", IEEE NUCL S, 48(3), 2001, pp. 750-755

Abstract

The diagnostic potential of brain SPECT imaging is limited by its low spatial resolution. We propose an iterative reconstruction technique that is based on the conjugate gradient (CG) algorithm and offers the possibility of improving the spatial resolution of the SPECT activity map of a patient, provided that an MR scan of the same patient is available. The SPECT data are reconstructed twice. The first reconstruction is to permit an accurate coregistration of the MR image to the SPECT one. Then, thiscoregistered MR image is used as the starting point for the CG algorithm, which solves a "shifted problem. " While the iterations are carried out, theMR signal of low spatial frequency is replaced by the SPECT activity. However, the high spatial frequency anatomical features contained in the MR image are weakly affected by the SPECT projector-back-projector operator. Theyremain in the iterates and increase their diagnostic potential. If an appropriate number of iterations is performed, quantitation is not significantly affected.

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Documento generato il 25/01/20 alle ore 18:35:08