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Titolo:
Realistic Monte Carlo simulation of Ga-67SPECT imaging
Autore:
Moore, SC; El Fakhri, G;
Indirizzi:
Harvard Univ, Sch Med, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 vard Univ, Sch Med, Boston, MA 02115 USA Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA Brigham & Womens Hosp Boston MA USA 02115 pt Radiol, Boston, MA 02115 USA
Titolo Testata:
IEEE TRANSACTIONS ON NUCLEAR SCIENCE
fascicolo: 3, volume: 48, anno: 2001,
parte:, 2
pagine: 720 - 724
SICI:
0018-9499(200106)48:3<720:RMCSOG>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
PHANTOM;
Keywords:
gallium-67; Monte Carlo methods; simulation; single photon emission computed tomography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Engineering, Computing & Technology
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Moore, SC Harvard Univ, Sch Med, Boston, MA 02115 USA Harvard Univ BostonMA USA 02115 Sch Med, Boston, MA 02115 USA
Citazione:
S.C. Moore e G. El Fakhri, "Realistic Monte Carlo simulation of Ga-67SPECT imaging", IEEE NUCL S, 48(3), 2001, pp. 720-724

Abstract

We describe a comprehensive Monte Carlo program tailored for efficient simulation of realistic Ga-67 SPECT imaging through the entire range of photonemission energies. Our approach incorporates several new features developed by us and by others. It is now being used to optimize and evaluate the performance of various methods of compensating for photon scatter, attenuation, and nonstationary distance- and energy-dependent detector resolution. Improvements include 1) the use of a numerical torso phantom with accurate organ source and attenuation maps obtained by segmenting CT images of a Radiology Support Devices anthropormorphic heart/thorax phantom, modified to include eight axillary lymph nodes; 2) accelerated photon propagation through the attenuator using a variant of the maximum rectangular region algorithm of Suganuma and Ogawa; and 3) improved variance reduction using modified spatial sampling for simulation of large-angle collimator penetration, scatter, and lead X-rays. Very-high-count projections were simulated in 55 energywindows spaced irregularly in the range 60-370 keV, these essentially noise-free images were used as a basis for generating Poisson noise realizations characteristic of 72-h postinjection Ga-67 studies. Comparisons of spatial and energy distributions demonstrated good agreement between data experimentally measured from the RSD phantom and those simulated from the mathematical segmentation of the same phantom.

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Documento generato il 18/01/20 alle ore 01:55:23