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Titolo:
Bilateral medial temporal lobe damage does not affect lexical or grammatical processing: Evidence from amnesic patient HM
Autore:
Kensinger, EA; Ullman, MT; Corkin, S;
Indirizzi:
MIT, Dept Brain & Cognit Sci, Cambridge, MA 02139 USA MIT Cambridge MA USA 02139 pt Brain & Cognit Sci, Cambridge, MA 02139 USA MIT, Clin Res Ctr, Cambridge, MA 02139 USA MIT Cambridge MA USA 02139MIT, Clin Res Ctr, Cambridge, MA 02139 USA Georgetown Univ, Dept Neurosci, Washington, DC USA Georgetown Univ Washington DC USA niv, Dept Neurosci, Washington, DC USA Georgetown Univ, Dept Linguist, Washington, DC USA Georgetown Univ Washington DC USA niv, Dept Linguist, Washington, DC USA Massachusetts Gen Hosp, Nucl Magnet Resonance Ctr, Charlestown, MA USA Massachusetts Gen Hosp Charlestown MA USA nance Ctr, Charlestown, MA USA
Titolo Testata:
HIPPOCAMPUS
fascicolo: 4, volume: 11, anno: 2001,
pagine: 347 - 360
SICI:
1050-9631(2001)11:4<347:BMTLDD>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALZHEIMERS-DISEASE; SEMANTIC MEMORY; BRAIN POTENTIALS; HIPPOCAMPAL-FORMATION; DOUBLE DISSOCIATION; DECLARATIVE MEMORY; LANGUAGE; SYSTEM; COMPREHENSION; LOCALIZATION;
Keywords:
lexicon; grammar; language; global amnesia; longitudinal; declarative memory;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
76
Recensione:
Indirizzi per estratti:
Indirizzo: Kensinger, EA MIT, Dept Brain & Cognit Sci, E18-470,77 Massachusetts Ave, Cambridge, MA 02139 USA MIT E18-470,77 Massachusetts Ave Cambridge MA USA 02139 USA
Citazione:
E.A. Kensinger et al., "Bilateral medial temporal lobe damage does not affect lexical or grammatical processing: Evidence from amnesic patient HM", HIPPOCAMPUS, 11(4), 2001, pp. 347-360

Abstract

In the most extensive investigation to date of language in global amnesia,we acquired data from experimental measures and examined longitudinal datafrom standardized tests, to determine whether language function was preserved in the amnesic patient H.M. The experimental measures indicated that H.M. performed normally on tests of lexical memory and grammatical function, relative to age- and education-matched control participants. Longitudinal data from four Wechsler subtests (information, Comprehension, Similarities, and Vocabulary), that H.M. had taken 20 times between 1953 (preoperatively)and 2000, indicated consistent performance across time, and provided no evidence of a lexical memory decrement. We conclude that medial temporal lobestructures are not critical for retention and use of already acquired lexical information or for grammatical processing. They are, however, required for acquisition of lexical information, as evidenced in previous studies revealing H.M.'s profound impairment at learning new words. Hippocampus 2001;11:347-360. (C) 2001 Wiley-Liss, Inc.

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Documento generato il 04/04/20 alle ore 12:06:29