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Titolo:
Autologous chondrocyte transplantation in osteochondral lesions of the ankle joint
Autore:
Giannini, S; Buda, R; Grigolo, B; Vannini, F;
Indirizzi:
Univ Bologna, Ist Ortoped Rizzoli, I-40136 Bologna, Italy Univ Bologna Bologna Italy I-40136 toped Rizzoli, I-40136 Bologna, Italy
Titolo Testata:
FOOT & ANKLE INTERNATIONAL
fascicolo: 6, volume: 22, anno: 2001,
pagine: 513 - 517
SICI:
1071-1007(200106)22:6<513:ACTIOL>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
SURGICAL APPROACH; TALAR DOME; TALUS; DISSECANS; KNEE;
Keywords:
hyaline cartilage; ankle joint; autologous chondrocyte transplantation; talus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Giannini, S Univ Bologna, Ist Ortoped Rizzoli, Via GC Pupilli 1, I-40136 Bologna, Italy Univ Bologna Via GC Pupilli 1 Bologna Italy I-40136 na, Italy
Citazione:
S. Giannini et al., "Autologous chondrocyte transplantation in osteochondral lesions of the ankle joint", FOOT ANKL I, 22(6), 2001, pp. 513-517

Abstract

The aim of this study was to assess the repair of osteochondral defects ofthe ankle joint with hyaline cartilage. For this purpose we have been using a technique of autologous chondrocyte transplantation for osteochondral defects of the talus for the last two years. Until the method described in the paper, treatment methods proposed for the repair of cartilaginous defects have not been histologically effective inrestoring the hyaline cartilage sheath, and in all cases the neoformation of cartilage was of a fibrocartilaginous nature with varying cellular characteristics. Clinical and histological results obtained using this surgical technique have confirmed its validity. Furthermore, neither subjective nor objective complications have been reported. Less pain and better articular function have also been observed. According to the AOFAS score, an improvement from anaverage score of 32/100 points preop. to 91/100 points at 24 months of follow up was obtained. Laboratory data have confirmed the presence of reconstructed cartilage with chondrocytes and expression of collagen II, characteristic of hyaline cartilage.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 12:07:37