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Titolo:
Differences in pharmacotherapy and in glucose control of type 2 diabetes patients in two neighbouring towns: a longitudinal population-based study
Autore:
Olsson, J; Lindberg, G; Gottsater, M; Lindwall, K; Sjostrand, A; Tisell, A; Melander, A;
Indirizzi:
Malmo Univ Hosp, Med Res Ctr, NEPI Fdn, SE-20502 Malmo, Sweden Malmo Univ Hosp Malmo Sweden SE-20502 , NEPI Fdn, SE-20502 Malmo, Sweden Hosp Pharm, Jonkoping, Sweden Hosp Pharm Jonkoping SwedenHosp Pharm, Jonkoping, Sweden Malmo Univ Hosp, Med Res Ctr, Dept Community Med, SE-20502 Malmo, Sweden Malmo Univ Hosp Malmo Sweden SE-20502 munity Med, SE-20502 Malmo, Sweden Vetlanda Hlth Care Ctr, Vetlanda, Sweden Vetlanda Hlth Care Ctr VetlandaSweden Hlth Care Ctr, Vetlanda, Sweden Tranas Hlth Care Ctr, Tranas, Sweden Tranas Hlth Care Ctr Tranas SwedenTranas Hlth Care Ctr, Tranas, Sweden
Titolo Testata:
DIABETES OBESITY & METABOLISM
fascicolo: 4, volume: 3, anno: 2001,
pagine: 249 - 253
SICI:
1462-8902(200108)3:4<249:DIPAIG>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
RISK;
Keywords:
type 2 diabetes; pharmacoepidemiology; longitudinal study; oral anti-hyperglycaemic agents; insulin;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Olsson, J Malmo Univ Hosp, Med Res Ctr, NEPI Fdn, SE-20502 Malmo, Sweden Malmo Univ Hosp Malmo Sweden SE-20502 , SE-20502 Malmo, Sweden
Citazione:
J. Olsson et al., "Differences in pharmacotherapy and in glucose control of type 2 diabetes patients in two neighbouring towns: a longitudinal population-based study", DIABET OB M, 3(4), 2001, pp. 249-253

Abstract

Aim: To compare prescribing, dosage and blood glucose levels in patients with type 2 diabetes in two communities with differences in anti-hyperglycaemic drug utilization. Methods: A retrospective longitudinal (1984-1994) population-based study in two neighbour towns in southern Sweden, The mean prescribed daily dose was expressed as a fraction of the Defined Daily Dose (DDD) for each drug. Results: In town A, prescribing of oral agents and insulin was predominantly made by one specialized diabetes clinician, while in town B it was spread among several different general practitioners and one specialist, Altogether 44 636 medical visits by 2348 patients were identified. In each town, about 40% of the patients were treated without anti-hyperglycaemic drugs, about 40% with oral agents and about 20% with insulin. However, there were pronounced between-town differences in dosage and glucose control. The mean prescribed daily dose of sulphonylurea monotherapy decreased gradually from approximate to 0.7 to approximate to 0.5 DDD in town B but remained approximate to 0.8 DDD in town A. The proportion of patients on both sulphonylureaand metformin increased substantially in town A but not in town B. In these patients, the mean prescribed daily dose of sulphonylurea exceeded 1.0 DDD in both towns, although it decreased with time in town B. The mean prescribed daily dose of insulin increased from 1.05 to 1.2 DDD in town A but remained virtually unchanged at 0.95 DDD in town B. The mean fasting blood glucose was lower in town A than in town B both overall (7.7 vs. 8.8 mmol/l), in those treated without any anti-hyperglycaemic drugs (7.2 vs. 8.1 mmol/l), in those on sulphonylurea monotherapy (8.3 vs. 9.7 mmol/l) and in those treated with insulin (8.1 vs. 10.2 mmol/l). Conclusions: Glucose control in routine care was better when most patientswere treated by a diabetes specialist and were exposed to more intense pharmacotherapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 19:18:48