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Titolo:
Mechanisms of postnatal neurobiological development: Implications for human development
Autore:
Webb, SJ; Monk, CS; Nelson, CA;
Indirizzi:
Univ Minnesota, Dept Pediat, Inst Child Dev, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 ld Dev, Minneapolis, MN 55455 USA
Titolo Testata:
DEVELOPMENTAL NEUROPSYCHOLOGY
fascicolo: 2, volume: 19, anno: 2001,
pagine: 147 - 171
SICI:
8756-5641(2001)19:2<147:MOPNDI>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN PREFRONTAL CORTEX; CENTRAL-NERVOUS-SYSTEM; HUMAN CEREBRAL-CORTEX; QUANTITATIVE GOLGI ANALYSIS; HUMAN BRAIN-DEVELOPMENT; EXCITATORY AMINO-ACIDS; MAGNETIC-RESONANCE; PYRAMIDAL NEURONS; DENTATE GYRUS; VISUAL-CORTEX;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
95
Recensione:
Indirizzi per estratti:
Indirizzo: Nelson, CA Univ Minnesota, Dept Pediat, Inst Child Dev, 51 E River Rd, Minneapolis, MN 55455 USA Univ Minnesota 51 E River Rd Minneapolis MN USA 55455 55455 USA
Citazione:
S.J. Webb et al., "Mechanisms of postnatal neurobiological development: Implications for human development", DEV NEUROPS, 19(2), 2001, pp. 147-171

Abstract

This review focuses on the postnatal neuroanatomical changes that arise during the first years of human life. Development is characterized by 2 majororganizational periods. The first period begins at conception and includesthe major histogenetic events such as neurulation, proliferation, migration, and differentiation. It has been proposed that these events may be controlled by genetic and epigenetic events, which give rise to neural structures that are amenable to external influence. The second period is a time of reorganization in the human cortex. These events occur during gestation and continue postnatally, possibly through the 2nd decade of life. This stage is characterized by dendritic and axonal growth, synapse production, neuronal and synaptic pruning, and changes in neurotransmitter sensitivity. Although the initiation of these events is influenced by endogenous signals, further neural maturation is primarily influenced by exogenous signals. To illustrate both the progressive and regressive events during the postnatal period, we use examples from the development of the human cortex.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 09:50:58