Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Stress and development: Behavioral and biological consequences
Autore:
Bremner, JD; Vermetten, E;
Indirizzi:
Emory Univ, Sch Med, Atlanta, GA 30322 USA Emory Univ Atlanta GA USA 30322 mory Univ, Sch Med, Atlanta, GA 30322 USA Vet Adm Med Ctr, Atlanta, GA USA Vet Adm Med Ctr Atlanta GA USAVet Adm Med Ctr, Atlanta, GA USA
Titolo Testata:
DEVELOPMENT AND PSYCHOPATHOLOGY
fascicolo: 3, volume: 13, anno: 2001,
pagine: 473 - 489
SICI:
0954-5794(200122)13:3<473:SADBAB>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTICOTROPIN-RELEASING FACTOR; MESSENGER-RIBONUCLEIC-ACID; RAT DENTATE GYRUS; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; DEXAMETHASONE SUPPRESSION TEST; REGULATE POSTNATAL-DEVELOPMENT; MAJOR DEPRESSIVE DISORDER; CHILDHOOD SEXUAL ABUSE; CA3 PYRAMIDAL NEURONS; SINGLE-UNIT RESPONSE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
145
Recensione:
Indirizzi per estratti:
Indirizzo: Bremner, JD ECNRU Emory W, 1256 Briarcliff Rd, Atlanta, GA 30306 USA ECNRUEmory W 1256 Briarcliff Rd Atlanta GA USA 30306 0306 USA
Citazione:
J.D. Bremner e E. Vermetten, "Stress and development: Behavioral and biological consequences", DEV PSYCHOP, 13(3), 2001, pp. 473-489

Abstract

Childhood abuse is an important public health problem; however, little is known about the effects of abuse on the brain and neurobiological development. This article reviews the behavioral and biological consequences of childhood abuse and places them in a developmental context. Animal studies showthat both positive and negative events early in life can influence neurobiological development in unique ways. Early stressors such as maternal separation result in lasting effects on stress-responsive neurobiological systems, including the hypothalamic-pituitary-adrenal (HPA) axis and noradrenergic systems. These studies also implicate a brain area involved in learning and memory, the hippocampus. in the long-term consequences of early stress. Clinical studies of patients with a history of abuse also implicate dysfunction in the HPA axis and the noradrenergic and hippocampal systems however,there are multiple questions related to chronicity of stress, developmental epoch at the time of the stressor, presence of stress-related psychiatricdisorders including posttraumatic stress disorder and depression, and psychological factors mediating the response to trauma that need to be addressed in this field of research. Understanding the effects of abuse on the development of the brain and neurobiology will nevertheless have important treatment and policy implications.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 16:52:01