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Titolo:
Umbilical cord blood transplants
Autore:
Gluckman, E; Locatelli, F;
Indirizzi:
Hop St Louis, Dept Hematol & Bone Marrow Transplant, F-75475 Paris 10, France Hop St Louis Paris France 10 Marrow Transplant, F-75475 Paris 10, France Policlin San Matteo, IRCCS, Pediat Clin, I-27100 Pavia, Italy Policlin SanMatteo Pavia Italy I-27100 ediat Clin, I-27100 Pavia, Italy
Titolo Testata:
CURRENT OPINION IN HEMATOLOGY
fascicolo: 6, volume: 7, anno: 2000,
pagine: 353 - 357
SICI:
1065-6251(200011)7:6<353:UCBT>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
EX-VIVO EXPANSION; HEMATOPOIETIC PROGENITOR CELLS; VERSUS-HOST DISEASE; BONE-MARROW; CD34(+) CELLS; PERIPHERAL-BLOOD; SELF-RENEWAL; STEM-CELLS; HLA; CHILDREN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Gluckman, E Hop St Louis, Dept Hematol & Bone Marrow Transplant, 1 Ave Claude Vellefaux, F-75475 Paris 10, France Hop St Louis 1 Ave Claude VellefauxParis France 10 0, France
Citazione:
E. Gluckman e F. Locatelli, "Umbilical cord blood transplants", CURR OPIN H, 7(6), 2000, pp. 353-357

Abstract

With the establishment of cord blood banks, the number of related and unrelated umbilical cord blood transplants is increasing worldwide. Close linkshave been established with the cord blood banks. Available data showed that Umbilical cord blood transplants offer overall results comparable to those obtained with related or unrelated bone marrow transplants. Several differences were found: engraftment with cord blood was delayed, resulting in anincreased incidence of early transplant complications, and the incidence of acute and chronic graft-versus-host disease was significantly reduced with cord blood grafts, even in HLA-mismatched transplants and in adults. In patients with leukemia, the rate of relapse appeared to be similar to that documented in bone marrow transplant recipients. These data confirm the potential benefit of using umbilical cord blood hematopoietic stem cells for allogeneic transplants. Curr Opin Hematol 2000,7:353-357 (C) 2000 Lippincott Williams & Wilkins, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 18:24:15