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Titolo:
Chronic myeloid leukemia with a rare variant Philadelphia translocation: t(9;10;22)(q34;q22;q11)
Autore:
Emberger, W; Behmel, A; Tschernigg, M; Seewann, HL; Petek, E; Kroisel, PM; Wagner, K;
Indirizzi:
Graz Univ, Inst Med Biol & Human Genet, A-8010 Graz, Austria Graz Univ Graz Austria A-8010 d Biol & Human Genet, A-8010 Graz, Austria Landeskrankenhaus Furstenfeld, Dept Hematol, A-8280 Furstenfeld, Austria Landeskrankenhaus Furstenfeld Furstenfeld Austria A-8280 enfeld, Austria
Titolo Testata:
CANCER GENETICS AND CYTOGENETICS
fascicolo: 1, volume: 129, anno: 2001,
pagine: 76 - 79
SICI:
0165-4608(200108)129:1<76:CMLWAR>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE NONLYMPHOCYTIC LEUKEMIA; CHRONIC MYELOGENOUS LEUKEMIA; ACUTE LYMPHOBLASTIC-LEUKEMIA; CHROMOSOMAL TRANSLOCATIONS; MYELODYSPLASTIC SYNDROMES; BCR GENE; ABNORMALITIES; AML; REARRANGEMENT; FLUORESCENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Emberger, W Graz Univ, Inst Med Biol & Human Genet, Harrochgasse 21-8, A-8010 Graz, Austria Graz Univ Harrochgasse 21-8 Graz Austria A-8010 Graz, Austria
Citazione:
W. Emberger et al., "Chronic myeloid leukemia with a rare variant Philadelphia translocation: t(9;10;22)(q34;q22;q11)", CANC GENET, 129(1), 2001, pp. 76-79

Abstract

We report a 59-year-old, male, chronic myeloid leukemia patient with a rare variant Philadelphia (Ph) translocation t(9;10;22)(q34;q22;q11). Fluorescence in situ hybridization with whole chromosome paints was used to confirmthe cytogenetic findings. With a BCR/ABL-specific probe. the known rearrangement on the derivative chromosome 22 was found. The prognostic implications as well as the relevance of the additional breakpoint region 10q22 are discussed. (C) 2001 Elsevier Science Inc. All rights reserved.

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Documento generato il 29/11/20 alle ore 16:06:08