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Titolo:
The antiulcerative effect of Thai Musa species in rats
Autore:
Pannangpetch, P; Vuttivirojana, A; Kularbkaew, C; Tesana, S; Kongyingyoes, B; Kukongviriyapan, V;
Indirizzi:
Khon Kaen Univ, Fac Med, Dept Pharmacol, Khon Kaen 40002, Thailand Khon Kaen Univ Khon Kaen Thailand 40002 macol, Khon Kaen 40002, Thailand Khon Kaen Univ, Fac Med, Dept Pathol, Khon Kaen 40002, Thailand Khon Kaen Univ Khon Kaen Thailand 40002 athol, Khon Kaen 40002, Thailand Khon Kaen Univ, Fac Med, Dept Parasitol, Khon Kaen 40002, Thailand Khon Kaen Univ Khon Kaen Thailand 40002 sitol, Khon Kaen 40002, Thailand
Titolo Testata:
PHYTOTHERAPY RESEARCH
fascicolo: 5, volume: 15, anno: 2001,
pagine: 407 - 410
SICI:
0951-418X(200108)15:5<407:TAEOTM>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLANTAIN BANANA; PROSTAGLANDINS;
Keywords:
Musa sapientum; banana; antipeptic ulcer; gastroprotective;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Pannangpetch, P Khon Kaen Univ, Fac Med, Dept Pharmacol, Khon Kaen 40002, Thailand Khon Kaen Univ Khon Kaen Thailand 40002 40002, Thailand
Citazione:
P. Pannangpetch et al., "The antiulcerative effect of Thai Musa species in rats", PHYTOTHER R, 15(5), 2001, pp. 407-410

Abstract

Bananas are reported to have an antipeptic ulcer effect, however, the beneficial action can be affected by many factors, including the variety. Our study was undertaken to investigate the antipeptic ulcer effect of the Palo and Horn varieties of banana, grown and consumed in the northeast of Thailand. Indomethacin and acetic acid-induced gastric lesions in rats were employed as models of peptic ulcer disease. The lengths of gastric lesions in the glandular part of the stomach were measured for the assessment of the protective effect of bananas. The healing effect was studied by histological examination of the ulcerated area. The lesions in rats treated with the extract of banana were significantly less dominant than those of the control. The average length of total lesions of rats treated with an extract of Palo or Horn bananas at a dose of 1.0 g/kg/d for 3 days prior to indomethacin administration were 4.47 +/- 1.2 and 1.87 +/- 0.44 nun, respectively, whereasthose observed in the control rats were 14.56 +/- 2.43 mm. In the ulcer-healing model, only the Hom-banana-extract-treated group showed a beneficial effect which manifested as a milder degree of histological change than thatof the indomethacin-induced-chronic-ulcer control group. However, in acetic acid-induced ulcers, the histological changes of every group were similar. The present findings indicate that bananas of different varieties have varying antipeptic ulcer effects. The extracts of Palo and Hom bananas have aprominent gastroprotective effect, whereas only the extract of Hom banana had an observed ulcer-healing effect. Copyright @ 2001 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 13:06:15