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Titolo:
Autonomic insufficiency as a factor contributing to dialysis-induced hypotension
Autore:
Sato, M; Horigome, I; Chiba, S; Furuta, T; Miyazaki, M; Hotta, O; Suzuki, K; Noshiro, H; Taguma, Y;
Indirizzi:
Sendai Shakaihoken Hosp, Dept Nephrol, Sendai, Miyagi, Japan Sendai Shakaihoken Hosp Sendai Miyagi Japan phrol, Sendai, Miyagi, Japan
Titolo Testata:
NEPHROLOGY DIALYSIS TRANSPLANTATION
fascicolo: 8, volume: 16, anno: 2001,
pagine: 1657 - 1662
SICI:
0931-0509(200108)16:8<1657:AIAAFC>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
POWER SPECTRAL-ANALYSIS; HEART-RATE-VARIABILITY; CHRONIC-RENAL-FAILURE; HEMODIALYSIS; NEUROPATHY;
Keywords:
autonomic insufficiency; chronic renal failure; diabetic nephropathy; dialysis-induced hypotension; [I-123]-MIBG myocardial scintigraphy; power spectral analysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Sato, M 2-16-506 Hasekura Machi,Aoba Ku, Sendai, Miyagi 9800824, Japan 2-16-506 Hasekura Machi,Aoba Ku Sendai Miyagi Japan 9800824 Japan
Citazione:
M. Sato et al., "Autonomic insufficiency as a factor contributing to dialysis-induced hypotension", NEPH DIAL T, 16(8), 2001, pp. 1657-1662

Abstract

Background. Autonomic insufficiency is considered a factor that contributes to dialysis-induced hypotension (DIH). However, the relationship between the two conditions has not been fully elucidated. Methods. We investigated 44 haemodialysis patients using [I-123]-meta-iodobenzylguanidine (MIBG) scintigraphy and power-spectral analysis (PSA) of heart rate variability. The patients were divided into four groups: a diabetic group with DIH, a diabetic group without DIH, a non-diabetic group with DIH, and a nondiabetic group without DIH. In these groups the heart to mediastinum average count rate (H/M), MIBG washout rate, and low- and high-frequency components of PSA were compared. Results. From the [I-123]-MIBG scintigraphy, for both early and delayed images, H/M of the groups with DIH were lower than in groups without DIH, in both diabetics and non-diabetics (P<0.05). For the early images, H/M of thediabetic groups were lower than in the non-diabetic groups, in the groups both with and without DIH (P<0.01). For the delayed images, H/M of the diabetic group was lower than in the nondiabetic group, in the groups with DIH (P<0.05). The MIBG washout rate was the highest in the diabetic group with DIH (P<0.05 rs diabetic and non-diabetic groups without DIH). The PSA of heart rate variability showed a good discrimination of the low-frequency component between the non-diabetic patients with and without DIH (P < 0.05). Mean ultrafiltration volume and its rate were not different among the four groups. Conclusion. Autonomic insufficiency is more severe in patients with DIH than in those without, and its degree may be enhanced in diabetic patients. For the management of DIH, special care should be addressed not only to dry weight but also to autonomic insufficiency.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 08:13:54