Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Analysis of theaflavins in biological fluids using liquid chromatography-electrospray mass spectrometry
Autore:
Mulder, TPJ; van Platerink, CJ; Schuyl, PJW; van Amelsvoort, JMM;
Indirizzi:
Unilever Res Labs Vlaardingen, Unilever Hlth Inst, NL-3130 AC Vlaardingen,Netherlands Unilever Res Labs Vlaardingen Vlaardingen Netherlands NL-3130AC erlands Unilever Res Labs Vlaardingen, Cent Analyt Sci, Vlaardingen, Netherlands Unilever Res Labs Vlaardingen Vlaardingen Netherlands ngen, Netherlands
Titolo Testata:
JOURNAL OF CHROMATOGRAPHY B
fascicolo: 2, volume: 760, anno: 2001,
pagine: 271 - 279
SICI:
1387-2273(20010905)760:2<271:AOTIBF>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
LC-MS ANALYSIS; GREEN TEA; FLAVONOL GLYCOSIDES; HUMAN PLASMA; CATECHINS; POLYPHENOLS; EXTRACTS; HPLC; ISOFLAVONES; COMPONENTS;
Keywords:
theaflavins;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Mulder, TPJ Unilever Res Labs Vlaardingen, Unilever Hlth Inst, POB 114, NL-3130 AC Vlaardingen, Netherlands Unilever Res Labs Vlaardingen POB 114 Vlaardingen Netherlands NL-3130 AC
Citazione:
T.P.J. Mulder et al., "Analysis of theaflavins in biological fluids using liquid chromatography-electrospray mass spectrometry", J CHROMAT B, 760(2), 2001, pp. 271-279

Abstract

A HPLC-MS procedure for the sensitive and specific analysis of the black tea flavonoid theaflavin in human plasma and urine was developed. Levels were measured after enzymatic deconjugation, extraction into ethyl acetate, and separation by HPLC, using tandem mass spectrometry as a detecting system. Two healthy volunteers consumed 700 mg theaflavins, equivalent to about 30cups of black tea. The maximum concentration detected in blood plasma was 1.0 mug l(-1) in a sample collected after 2 h. The concentration in urine also peaked after 2 h at 4.2 mug l(-1). Hence, only minute amounts of theaflavins can be detected in plasma and urine samples of healthy volunteers after ingestion. (C) 2001 Elsevier Science BV All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/01/20 alle ore 20:00:42