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Titolo:
Incidence of cervical node involvement in metastatic cutaneous malignancy involving the parotid gland
Autore:
OBrien, CJ; McNeil, EB; McMahon, JD; Pathak, I; Lauer, CS;
Indirizzi:
Royal Prince Alfred Hosp, Dept Head & Neck Surg, Sydney, NSW 2042, Australia Royal Prince Alfred Hosp Sydney NSW Australia 2042 y, NSW 2042, Australia
Titolo Testata:
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
fascicolo: 9, volume: 23, anno: 2001,
pagine: 744 - 748
SICI:
1043-3074(200109)23:9<744:IOCNII>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
NECK DISSECTION; SKIN-CANCER; HEAD; CARCINOMA; MELANOMA;
Keywords:
skin cancer; parotid; metastatic SCC; metastatic melanoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: O'Brien, CJ Royal Prince Alfred Hosp, Dept Head & Neck Surg, 100 Carillon Ave, Sydney,NSW 2042, Australia Royal Prince Alfred Hosp 100 Carillon Ave Sydney NSW Australia 2042
Citazione:
C.J. O'Brien et al., "Incidence of cervical node involvement in metastatic cutaneous malignancy involving the parotid gland", HEAD NECK, 23(9), 2001, pp. 744-748

Abstract

Background. The parotid lymph nodes represent an important group of nodes at risk for metastatic involvement from cutaneous malignancies of the head and neck. When treating patients with metastatic disease in the parotid gland it has been our custom to also remove the lymph nodes of the neck on thebasis that these nodes represent other nodal groups at risk for metastaticInvolvement. The aim of this study Is to determine the incidence of cervical node involvement among patients with clinical metastatic SCC or melanomaof the parotid to determine whether treatment of the clinically negative neck is warranted. Methods. The study group consists of 123 prospectively accessioned patients with clinical metastatic cutaneous squamous cell carcinoma (SCC) (n = 73)or melanoma (n = 50) involving the parotid gland and a minimum of 2 years of follow up, irrespective of the clinical status of the neck. Results. Among 73 patients with metastatic SCC In the parotid, 19 (26%) had clinical neck involvement, and 16 of these were pathologically positive (84%). A total of 37 patients had elective neck dissections, and 13 were pathologically positive, which is an overall rate of 52% neck involvement among patients having neck dissection. Among 50 patients with metastatic melanoma in the parotid, 19 (38%) patients were initially seen with clinical neckdisease, and all were pathologically positive. Among 31 patients with clinically negative necks, 26 had neck dissections and seven had positive nodes(27%). Overall, 58% of patients with melanoma who had a neck dissection had positive nodes. Conclusion. Patients with metastatic cutaneous SCC and melanoma involving the parotid gland had a high incidence of clinical (261% and 38%, respectively) and occult neck disease (35% and 27%). Treatment of the clinically negative neck in the presence of clinical metastatic parotid cancer should be considered to reduce the likelihood of failure in cervical nodes, to definethe extent of disease, and to assist with patient selection for adjuvant therapy. (C) 2001 John Wiley & Sons, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 18:05:54