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Titolo:
Painless thyroiditis associated with severe inflammatory reactions in amyloid goiter: A case report
Autore:
Bando, Y; Ushiogi, Y; Toya, D; Tanaka, N; Fujisawa, M;
Indirizzi:
Fukui Ken Saiseikai Hosp, Dept Internal Med, Fukui 9188503, Japan Fukui Ken Saiseikai Hosp Fukui Japan 9188503 l Med, Fukui 9188503, Japan
Titolo Testata:
ENDOCRINE JOURNAL
fascicolo: 3, volume: 48, anno: 2001,
pagine: 323 - 329
SICI:
0918-8959(200106)48:3<323:PTAWSI>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
GIANT-CELL THYROIDITIS; HASHIMOTOS-THYROIDITIS; SUBACUTE THYROIDITIS; SYSTEMIC AMYLOIDOSIS; SERUM INTERLEUKIN-6; ACUTE EXACERBATION; THYROTOXICOSIS; DISEASE; PATIENT;
Keywords:
painless thyroiditis; amyloid goiter; subacute thyroiditis-like syndrome; interleukin-6 (IL-6); rheumatoid arthritis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Bando, Y Fukui Ken Saiseikai Hosp, Dept Internal Med, Funabashi 7-1,Wadanaka Machi,Fukui 9188503, Japan Fukui Ken Saiseikai Hosp Funabashi 7-1,Wadanaka Machi Fukui Japan 9188503
Citazione:
Y. Bando et al., "Painless thyroiditis associated with severe inflammatory reactions in amyloid goiter: A case report", ENDOCR J, 48(3), 2001, pp. 323-329

Abstract

We report the case of a 64-year-old woman with rheumatoid arthritis (RA) associated with high grade fever, malaise, and painless swelling of thyroid gland. Laboratory findings showed severe systemic inflammatory reactions, including increases in various cytokines such as IL-6. Gallium-67 citrate imaging revealed intense uptake in the painlessly enlarged thyroid gland. Histologically, biopsied specimens of thyroid showed diffuse amyloid infiltrations, which included amyloid A (AA) protein. Biopsies of rectum and stomachrevealed similar amyloid depositions, indicating that the amyloid had a secondary origin, potentially due to RA. All clinical symptoms were relieved by intravenous pulsatile administration of methylprednisolone followed by oral prednisone, resulting in prolonged hypothyroid status. To our knowledge, this is the first case report in Japan describing painless thyroiditis with severe inflammatory reactions in amyloid goiter.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 09:52:12