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Titolo:
The role of passive immunization in HIV-positive patients - A case report
Autore:
Veljkovic, V; Metlas, R; Jevtovic, D; Stringer, WW;
Indirizzi:
Univ Calif Los Angeles, Sch Med, Harbor UCLA Med Ctr, Torrance, CA 90509 USA Univ Calif Los Angeles Torrance CA USA 90509 Ctr, Torrance, CA 90509 USA Diapharm, Guernsey, England Diapharm Guernsey EnglandDiapharm, Guernsey, England Inst VINCA, Belgrade, Yugoslavia Inst VINCA Belgrade YugoslaviaInst VINCA, Belgrade, Yugoslavia Inst Infect & Trop Dis, Belgrade, Yugoslavia Inst Infect & Trop Dis Belgrade Yugoslavia op Dis, Belgrade, Yugoslavia
Titolo Testata:
CHEST
fascicolo: 2, volume: 120, anno: 2001,
pagine: 662 - 666
SICI:
0012-3692(200108)120:2<662:TROPII>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNODEFICIENCY-VIRUS TYPE-1; VASOACTIVE-INTESTINAL-PEPTIDE; ENVELOPE GLYCOPROTEIN GP120; 2ND CONSERVED REGION; HUMAN AUTOANTIBODY; MUSCULAR EXERCISE; INFECTION; ANTIBODIES; NEUTRALIZATION; IGG;
Keywords:
aerobic exercise; AIDS; anti-vasoactive intestinal peptide/NTM antibodies; HIV; Ig preparations; passive immunization; tuberculosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Stringer, WW Univ Calif Los Angeles, Sch Med, Harbor UCLA Med Ctr, 1000 W Carson St,Box459, Torrance, CA 90509 USA Univ Calif Los Angeles 1000 W Carson St,Box 459 Torrance CA USA 90509
Citazione:
V. Veljkovic et al., "The role of passive immunization in HIV-positive patients - A case report", CHEST, 120(2), 2001, pp. 662-666

Abstract

An HIV positive patient presented with pulmonary tuberculosis as her AIDS-defining diagnosis in 1993 and was effectively treated with 12 months of standard antituberculosis medications (isoniazide, rifampin, and pyrazinamidefor 2 months). She received zidovudine for 6 weeks at the time of her diagnosis; however, because of patient preference, she has not received subsequent standard HIV medications (7 years). Her CD4 count at the time of diagnosis (1993) was 297/muL. Monthly passive immunotherapy was administered (fresh frozen plasma from HIV-negative blood donors with a significant titer for the anti-vasoactive intestinal peptide [VIP]/NTM antibody) from December 1993 to June 1994. Her CD4 count increased to > 400/muL during the passive immunotherapy and has remained stable for the past 6 years. The rational for the use of anti-VIP/NTM antibodies preparations in HIV, the possible modeof action of anti-VIP/NTM antibodies, the use of Ig preparations, and the role of exercise as a natural source of anti-VIP/NTM antibodies are discussed. This case report supports the potential therapeutic use of anti-VIP antibodies for treatment of HIV disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 03:09:19