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Titolo:
Home oximetry studies for diagnosis of sleep apnea/hypopnea syndrome - Limitation of memory storage capabilities
Autore:
Wiltshire, N; Kendrick, AH; Catterall, JR;
Indirizzi:
Bristol Royal Infirm & Gen Hosp, Dept Resp Med, Bristol BS2 8HW, Avon, England Bristol Royal Infirm & Gen Hosp Bristol Avon England BS2 8HW von, England
Titolo Testata:
CHEST
fascicolo: 2, volume: 120, anno: 2001,
pagine: 384 - 389
SICI:
0012-3692(200108)120:2<384:HOSFDO>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
APNEA-HYPOPNEA SYNDROME; DAYTIME SLEEPINESS;
Keywords:
polysomnography; pulse oximetry; sleep apnea;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Kendrick, AH Bristol Royal Infirm & Gen Hosp, Dept Resp Med, Bristol BS2 8HW, Avon, England Bristol Royal Infirm & Gen Hosp Bristol Avon England BS28HW
Citazione:
N. Wiltshire et al., "Home oximetry studies for diagnosis of sleep apnea/hypopnea syndrome - Limitation of memory storage capabilities", CHEST, 120(2), 2001, pp. 384-389

Abstract

Background: Memory oximeters enable di agnostic studies for sleep apnea hypopnea syndrome (SAHS) to be performed in the home. However, memory capabilities may be limited. Study Objectives: To compare a pulse oximeter used at home with an 8-h memory, storing data every 12 s, and in the laboratory, with on-line recordingevery 2 s. Design: Prospective cohort study. Setting: Patients' homes and a sleep laboratory. Patients: One hundred patients with suspected SAHS. Measurements: Home oximetry and a laboratory full polysomnography. The number of greater than or equal to 4% dips in pulse oximetric saturation (Spo(2)) was calculated for each study. Daytime sleepiness was assessed by the Epworth Sleepiness Scale (ESS) score. Results: The mean dips per hour were 5.3/h (range, 0 to 53/h) for home studies and 13.4/h (range, 0 to 106/h) for laboratory studies; the relationship between home and laboratory studies was as follows: home = (0.4 x laboratory) - 0.01 +/- 11.2; r(2) = 0.64. Mean difference was 8.4/h (- 2.5 to + 77.9/h), which correlated with the mean of the measurements. At a cutoff point of 10/h, 52 studies were both negative and 13 studies were both positive. Nineteen home studies were false-negatives. Sensitivity was 0.41, and specificity was 1.0. In these 19 studies, 7 patients had an ESS score > 10 and 4 patients had an ESS score > 14. To confirm that differences were due to different sampling rates, 16 additional patients had on-line data and storeddata collected simultaneously in the laboratory. Mean clips per hour were 3.2/h (range, 0.1 to 18.3/h) for the stored data and 8.34/h (0.2 to 22.8/h)for on-line data; the relationship being stored was as follows: 0.5 on-line - 1.17 +/- 2.6; r(2) = 0.69. Mean difference was 5.2/h (0.04 to 15.4 h), which correlated with the mean of the measurements. Conclusion: Home studies using a memory storage pulse oximeter may underestimate the number of hypo)dc dips, probably due to sampling rates. Clinically significant hypoxic SAHS may therefore be missed.

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Documento generato il 11/08/20 alle ore 15:41:30