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Titolo:
Retinal ischemia and embolism - Etiologies and outcomes based on a prospective study
Autore:
Babikian, V; Wijman, CAC; Koleini, B; Malik, SN; Goyal, N; Matjucha, ICA;
Indirizzi:
Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA Boston Univ Boston MA USA 02118 ch Med, Dept Neurol, Boston, MA 02118 USA Boston Univ, Sch Med, Dept Ophthalmol, Boston, MA 02118 USA Boston Univ Boston MA USA 02118 ed, Dept Ophthalmol, Boston, MA 02118 USA
Titolo Testata:
CEREBROVASCULAR DISEASES
fascicolo: 2, volume: 12, anno: 2001,
pagine: 108 - 113
SICI:
1015-9770(2001)12:2<108:RIAE-E>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
CAROTID-ARTERY DISEASE; AMAUROSIS FUGAX; OCCLUSION; STENOSIS; STROKE;
Keywords:
retina; ischemia; embolism;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Babikian, V Boston Univ, Boston VA Med Ctr, Dept Neurol, Sch Med, 150 S Huntington Ave, Boston, MA 02130 USA Boston Univ 150 S Huntington Ave Boston MA USA 02130 02130 USA
Citazione:
V. Babikian et al., "Retinal ischemia and embolism - Etiologies and outcomes based on a prospective study", CEREB DIS, 12(2), 2001, pp. 108-113

Abstract

Objectives: To identify the most likely mechanisms of retinal ischemia andembolism in a hospital-referred population, and to determine the frequencyof recurrent vascular events during the 3-month period following initial presentation. Methods. Consecutive patients presenting to 2 tertiary medicalcenters and their outpatient clinics were prospectively enrolled over a 22-month period. Eligible patients presented with histories of transient or permanent monocular visual loss, or had evidence of asymptomatic retinal embolism on routine ophthalmological examination. They underwent a rapid and standardized evaluation that included imaging studies as well as blood tests, and follow-up was obtained at 1 and 3 months. Results: Seventy-seven patients were enrolled. Enrollment diagnoses consisted of amaurosis fugax (n = 32), asymptomatic retinal embolism (n = 34), and central or branch retinal artery occlusion (n = 11). Eight different presumed etiologies of retinal artery distribution embolism or hypoperfusion were identified. Extracranial internal carotid artery occlusion or more than 50% stenosis was observed in17/77 (22.1%) cases, making it the largest etiologic subgroup. Uncommon but treatable conditions were identified in 8/77 (10.4%) patients, and an etiologic diagnosis could not be made in 35/77 (45.5%) patients. Recurrent events occurred in, respectively, 14/77 (18.2%) and 6/73 (8.2%) patients at the 1- and 3-month follow-ups. They included 2 infarcts and 2 deaths; ischemic events of the retina were more common than those involving the brain. Conclusion: Severe stenosis of the extracranial internal carotid artery is themost common identified condition associated with retinal ischemia and embolism, but a variety of other, potentially treatable, conditions can be diagnosed if appropriate and specific evaluations are conducted. The frequency of recurrent vascular ischemic events is highest during the 1st month of follow-up and decreases during the 2nd and 3rd months. Recurrences range fromrelatively innocuous episodes of amaurosis fugax to vascular death. Copyright (C) 2001 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 03:27:49