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Titolo:
A pharmacoeconomic analysis of the impact of therapeutic drug monitoring in adult patients with generalized tonic-clonic epilepsy
Autore:
Rane, CT; Dalvi, SS; Gogtay, NJ; Shah, PU; Kshirsagar, NA;
Indirizzi:
KEM Hosp, Dept Neurol, Parel 400012, Mumbai, India KEM Hosp Parel Mumbai India 400012 pt Neurol, Parel 400012, Mumbai, India TN Med Coll & BYL Nair Hosp, Dept Clin Pharmacol, Mumbai 400008, India TN Med Coll & BYL Nair Hosp Mumbai India 400008 ol, Mumbai 400008, India
Titolo Testata:
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
fascicolo: 2, volume: 52, anno: 2001,
pagine: 193 - 195
SICI:
0306-5251(200108)52:2<193:APAOTI>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Keywords:
epilepsy; pharmacoeconomics; therapeutic drug monitoring;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
6
Recensione:
Indirizzi per estratti:
Indirizzo: Kshirsagar, NA Seth GS Med Coll & KEM Hosp, Dept Clin Pharmacol, Mumbai 400012, India Seth GS Med Coll & KEM Hosp Mumbai India 400012 12, India
Citazione:
C.T. Rane et al., "A pharmacoeconomic analysis of the impact of therapeutic drug monitoring in adult patients with generalized tonic-clonic epilepsy", BR J CL PH, 52(2), 2001, pp. 193-195

Abstract

Aims To carry out a retrospective pharmacoeconomic analysis of the impact of therapeutic drug monitoring (TDM) in adult patients with generalized tonic-clonic epilepsy in an academic, non profit making organization. Methods Twenty-five patients who had undergone TDM were compared with 25 age, disease and duration of drug therapy matched controls who had not undergone TDM. Only direct costs were calculated. These included cost to the hospital of providing the TDM service, cost to the hospital per seizure saved,and cost to the patient per seizure saved. Results Patients undergoing TDM had much more effective seizure control (P= 0.00032, OR 4.846, 95% confidence interval 1.29,18.3), fewer adverse events, better earning and were more likely to be married than the control group. Conclusions In patients with adult onset epilepsy, a minimum of two drug estimations per year offers significant benefit in terms of better seizure control, fewer adverse events and greater chances of remission.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 03:00:24