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Titolo:
Thymectomy in myasthenia gravis
Autore:
Atance, PL; Aragoneses, FG; Mata, NM; Fontan, EG; Medina, DL; Gomez, JMN; Blanco, JLM; Palomino, EO; Gomez, EF;
Indirizzi:
Hosp Gen Univ Gregorio Maranon, Serv Cirugia Torac, Madrid 28007, Spain Hosp Gen Univ Gregorio Maranon Madrid Spain 28007 c, Madrid 28007, Spain Hosp Gen Univ Gregorio Maranon, Serv Neurol, Madrid 28007, Spain Hosp Gen Univ Gregorio Maranon Madrid Spain 28007 l, Madrid 28007, Spain
Titolo Testata:
ARCHIVOS DE BRONCONEUMOLOGIA
fascicolo: 5, volume: 37, anno: 2001,
pagine: 235 - 239
SICI:
0300-2896(200105)37:5<235:TIMG>2.0.ZU;2-L
Fonte:
ISI
Lingua:
SPA
Soggetto:
TRANSCERVICAL THYMECTOMY; THORACOSCOPIC THYMECTOMY; EXTENDED THYMECTOMY; EXPERIENCE; FOLLOW;
Keywords:
myasthenia gravis; thymectomy; thymoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Atance, PL Hosp Gen Univ Gregorio Maranon, Serv Cirugia Torac, Doctor Esquerdo 46, Madrid 28007, Spain Hosp Gen Univ Gregorio Maranon Doctor Esquerdo46 Madrid Spain 28007
Citazione:
P.L. Atance et al., "Thymectomy in myasthenia gravis", ARCH BRONCO, 37(5), 2001, pp. 235-239

Abstract

Objective: To analyze outcome after thymectomy in patients with myastheniagravis (MG). Material and methods: Thirty-five patients with MG underwent surgery in our service between June 1987 and June 1998. Ten had associated thymomas. Preoperative Osserman classification showed 2 at level I, 20 at level IIA, 11 at level IIB and 2 at level III. Extended thymectomy through a medial sternotomy was performed in all. Results: Postoperative complications developed in three patients (1 medullary aplasia, I postoperative reintubation, 1 myasthenic crisis). Mean follow-up was 89 months, with 22.8% achieving complete remission and 97.1% reporting improvements. The results were similar in the 10 patients with thymomas (20% full remission and 90% showing improvement). By DeFilippi classification, 22.8% were in class 1, 22.8% in class 2, 51.4% in class 3 and 2.8% inclass 4. By Osserman classification, 9 were in the same category before and after surgery, 12 had improved one level, 10 had improved 2 levels, 3 hadimproved 3 levels and 1 patient had improved 4 levels. Conclusion: Thymectomy is an appropriate therapeutic procedure in the multidisciplinary treatment of patients with MG and it is the approach of choice for patients with associated thymomas. The intra- and post-operative complication rate is low and the rate of clinical improvement is high.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 10:02:24