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Titolo:
Comparison of cyfra 21-1 and squamous cell carcinoma antigen in detecting nasopharyngeal carcinoma
Autore:
Lee, JK; Hsieh, JF; Tsai, SC; Ho, YJ; Sun, SS; Kao, CH;
Indirizzi:
China Med Coll Hosp, Dept Nucl Med, Taichung 400, Taiwan China Med Coll Hosp Taichung Taiwan 400 t Nucl Med, Taichung 400, Taiwan Jen Ai Hosp, Dept Radiol, Taichung, Taiwan Jen Ai Hosp Taichung TaiwanJen Ai Hosp, Dept Radiol, Taichung, Taiwan Taichung Vet Gen Hosp, Dept Nucl Med, Taichung, Taiwan Taichung Vet Gen Hosp Taichung Taiwan , Dept Nucl Med, Taichung, Taiwan Chi Mei Fdn Hosp, Dept Nucl Med, Tainan, Taiwan Chi Mei Fdn Hosp Tainan Taiwan Fdn Hosp, Dept Nucl Med, Tainan, Taiwan Show Chwan Mem Hosp, Dept Nucl Med, Changhua, Taiwan Show Chwan Mem Hosp Changhua Taiwan sp, Dept Nucl Med, Changhua, Taiwan
Titolo Testata:
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
fascicolo: 8, volume: 110, anno: 2001,
pagine: 775 - 778
SICI:
0003-4894(200108)110:8<775:COC2AS>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
TUMOR-MARKER; LUNG-CANCER; MONOCLONAL-ANTIBODIES; HEAD; NECK; CYTOKERATINS; DIAGNOSIS; SCC;
Keywords:
CYFRA 21-1; nasopharyngeal carcinoma; squamous cell carcinoma antigen;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Lee, JK China Med Coll Hosp, Dept Nucl Med, No 2,Yuh Der Rd, Taichung 400,Taiwan China Med Coll Hosp No 2,Yuh Der Rd Taichung Taiwan 400 0, Taiwan
Citazione:
J.K. Lee et al., "Comparison of cyfra 21-1 and squamous cell carcinoma antigen in detecting nasopharyngeal carcinoma", ANN OTOL RH, 110(8), 2001, pp. 775-778

Abstract

CYFRA 21-1 is a newly developed tumor marker that is especially useful fordetecting squamous cell carcinoma (SCC) of the lung. Squamous cell carcinoma antigen is a proven tumor marker that is especially useful for detectingSCC of the cervix. Our aim in this study was to compare the clinical valueof CYFRA 21-1 and SCC antigen in the detection of nasopharyngeal carcinoma(NPC). Serum levels of CYFRA 21-1 and SCC antigen were measured in 80 untreated NPC patients and 77 healthy controls. The cutoff values of CYFRA 21-1and SCC antigen, determined at the 95th percentile of the 77 healthy controls, were 2.48 ng/mL and 1.49 ng/mL, respectively. The results revealed that the mean serum value of only CYFRA 21-1 was significantly higher in the 80 NPC patients than in the 77 healthy controls, and the detection sensitivity of CYFRA 21-1 for NPC was significantly higher than that of SCC antigen. In conclusion, our results suggest that CYFRA 21-1 is a better tumor marker than SCC antigen for detection of NPC.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 12:45:49