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Titolo:
Analysis of the consistency of intraurethral prostaglandin E-1 (MUSE) during at-home use
Autore:
Mulhall, JP; Jahoda, AE; Ahmed, A; Parker, M;
Indirizzi:
Loyola Univ, Med Ctr, Stritch Sch Med, Dept Urol, Maywood, IL 60304 USA Loyola Univ Maywood IL USA 60304 ch Med, Dept Urol, Maywood, IL 60304 USA
Titolo Testata:
UROLOGY
fascicolo: 2, volume: 58, anno: 2001,
pagine: 262 - 266
SICI:
0090-4295(200108)58:2<262:AOTCOI>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRACAVERNOUS INJECTION THERAPY; MEDICATED URETHRAL SYSTEM; ERECTILE DYSFUNCTION; TRANSURETHRAL ALPROSTADIL; MEN; IMPOTENCE; EFFICACY; SAFETY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Mulhall, JP Loyola Univ, Med Ctr, Stritch Sch Med, Dept Urol, 2160 S 1st Ave, Maywood,IL 60304 USA Loyola Univ 2160 S 1st Ave Maywood IL USA 60304 d,IL 60304 USA
Citazione:
J.P. Mulhall et al., "Analysis of the consistency of intraurethral prostaglandin E-1 (MUSE) during at-home use", UROLOGY, 58(2), 2001, pp. 262-266

Abstract

Objectives. To determine the consistency of a successful response to intraurethral prostaglandin El (MUSE), an effective treatment for a proportion of patients with erectile dysfunction, during at-home use in men who had a successful response in the office, to define the factors that correlated with the consistency of the response, and to determine whether patients continued long-term use. Methods. The study group consisted of men with documented erectile dysfunction who had a successful response (grade 3 or 4 erection) to MUSE during an initial in-office dose. All enrollees completed a home diary assessing the treatment success during at least five medication administrations. Factors such as patient age, vascular risk factor status, and degree of in-officeresponse were prospectively evaluated as correlates of response consistency. Finally, patient follow-up was conducted in an attempt to define how many patients were continuing to use this medication as a long-term treatment modality. Results. Two hundred twelve patients underwent screening and 72 (34%) patients had in-office success. The overall per patient at-home consistency rate was 51%. None of the aforementioned factors correlated with the consistency of the response, At a mean of 9 months after beginning treatment, only 31% of the in-off ice responders were continuing to use MUSE. Conclusions. Although MUSE is an appropriate and safe treatment for many patients with erectile dysfunction, the lack of consistency is a significantconsideration. Clinicians should pay close attention to patient education in an effort to promote realistic expectations for MUSE therapy. Furthermore, the lack of consistency may significantly lower the patient's interest in continuing this treatment long term. UROLOGY 58: 262-266, 2001. (C) 2001,Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/04/20 alle ore 01:56:00