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Titolo:
Facile synthesis of glycotope bioisosteres bearing beta-D-galactoside moieties
Autore:
Liu, BC; Roy, R;
Indirizzi:
Univ Ottawa, Dept Chem, Ctr Res Biopharmaceut, Ottawa, ON K1N 6N5, Canada Univ Ottawa Ottawa ON Canada K1N 6N5 armaceut, Ottawa, ON K1N 6N5, Canada
Titolo Testata:
TETRAHEDRON
fascicolo: 32, volume: 57, anno: 2001,
pagine: 6909 - 6913
SICI:
0040-4020(20010806)57:32<6909:FSOGBB>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECOGNITION; GALECTINS; BINDING; LECTINS; LIGANDS; DESIGN;
Keywords:
multivalent effect; glycoconjugates; Sonogashira reaction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Roy, R Univ Ottawa, Dept Chem, Ctr Res Biopharmaceut, Ottawa, ON K1N 6N5, Canada Univ Ottawa Ottawa ON Canada K1N 6N5 t, Ottawa, ON K1N 6N5, Canada
Citazione:
B.C. Liu e R. Roy, "Facile synthesis of glycotope bioisosteres bearing beta-D-galactoside moieties", TETRAHEDRON, 57(32), 2001, pp. 6909-6913

Abstract

To investigate the relationship between the structural features and binding effectiveness involved in multiple protein-carbohydrate interactions, glycoconjugate analogues of limited flexibility, containing P-D-galactopyranoside moieties were synthesized in good yields using the Sonogashira reaction. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 12:46:34