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Titolo:
Vasospasm after subarachnoid hemorrhage - Interest in diffusion-weighted MR imaging
Autore:
Condette-Auliac, S; Bracard, S; Anxionnat, R; Schmitt, E; Lacour, JC; Braun, M; Meloneto, J; Cordebar, A; Yin, L; Picard, L;
Indirizzi:
CHU Nancy, Dept Diagnost & Intervent Neuroradiol, Nancy, France CHU NancyNancy France Diagnost & Intervent Neuroradiol, Nancy, France CHU Nancy, Dept Neurol, Nancy, France CHU Nancy Nancy FranceCHU Nancy, Dept Neurol, Nancy, France CMC Foch, Dept Neuroradiol, Suresnes, France CMC Foch Suresnes FranceCMC Foch, Dept Neuroradiol, Suresnes, France
Titolo Testata:
STROKE
fascicolo: 8, volume: 32, anno: 2001,
pagine: 1818 - 1824
SICI:
0039-2499(200108)32:8<1818:VASH-I>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOCAL CEREBRAL-ISCHEMIA; INTRACEREBRAL HEMORRHAGE; COEFFICIENT; STROKE; INJURY; RATS; ABNORMALITIES; HYPOGLYCEMIA; PERFUSION; REVERSAL;
Keywords:
magnetic resonance imaging, diffusion-weighted subarachnoid hemorrhage; vasospasm;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Bracard, S CHU Nancy, Hop Neurol, Serv Neuroradiol Diagnost & Therapeut, F-54035 Nancy, France CHU Nancy Nancy France F-54035 erapeut, F-54035 Nancy, France
Citazione:
S. Condette-Auliac et al., "Vasospasm after subarachnoid hemorrhage - Interest in diffusion-weighted MR imaging", STROKE, 32(8), 2001, pp. 1818-1824

Abstract

Background and Purpose-Vasospasm secondary to subarachnoid hemorrhage (SAH) is responsible for severe ischemic complications. Although effective, angioplasty must be performed at a very early stage to produce any clinical recovery. Diagnostic investigations to assess arterial narrowing (transcranial Doppler, angiography) or cerebral perfusion (xenon CT, single-photon emission CT) do not provide evidence of the extent of parenchymal ischemia. In stroke, diffusion-weighted MR imaging (DWI) appears to be the most sensitive procedure to detect cerebral ischemia. We studied asymptomatic vasospasm in patients with aneurysmal SAH to assess whether DWI provides predictive markers of silent ischemic lesions and/or progression toward symptomatic ischemia. Methods-Seven asymptomatic vasospasm patients (average blood velocity rates > 120 cm/s), 3 patients with symptomatic vasospasm, and 4 patients with SAH but without vasospasm were studied at regular intervals by DWI, and their apparent diffusion coefficients (ADCs) were calculated. Results-All patients with vasospasm including those without symptoms presented abnormalities on DWI with a reduction of the ADC prevalently in the white matter. No such abnormalities were observed in patients without vasospasm. The abnormalities on DWI resolved completely in 4 of the 7 patients, with no parenchymal lesion. Resolution was partial in 3 patients whose white matter still presented residual round, focal ischemic lesions. Conclusions-Being able to correlate abnormalities on DWI with parenchymal involvement in asymptomatic patients would be of considerable clinical significance. It is hoped that larger studies will be undertaken to determine whether the ADC has a reversibility threshold, because this would facilitatepatient management.

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Documento generato il 07/08/20 alle ore 06:52:44