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Titolo:
Race-ethnic disparities in the impact of stroke risk factors - The Northern Manhattan Stroke Study
Autore:
Sacco, RL; Boden-Albala, B; Abel, G; Lin, IF; Elkind, M; Hauser, WA; Paik, MC; Shea, S;
Indirizzi:
Columbia Univ, Coll Phys & Surg, Dept Neurol, New York, NY USA Columbia Univ New York NY USA Phys & Surg, Dept Neurol, New York, NY USA Columbia Univ, Coll Phys & Surg, Gertrude H Sergievsky Ctr, New York, NY USA Columbia Univ New York NY USA ertrude H Sergievsky Ctr, New York, NY USA Columbia Univ, Coll Phys & Surg, Div Epidemiol, New York, NY USA Columbia Univ New York NY USA ys & Surg, Div Epidemiol, New York, NY USA Columbia Univ, Coll Phys & Surg, Div Socio Med Sci, New York, NY USA Columbia Univ New York NY USA Surg, Div Socio Med Sci, New York, NY USA Columbia Univ, Coll Phys & Surg, Dept Med, Div Gen Med, New York, NY USA Columbia Univ New York NY USA g, Dept Med, Div Gen Med, New York, NY USA Columbia Univ, Coll Phys & Surg, Div Biostat, New York, NY USA Columbia Univ New York NY USA Phys & Surg, Div Biostat, New York, NY USA
Titolo Testata:
STROKE
fascicolo: 8, volume: 32, anno: 2001,
pagine: 1725 - 1731
SICI:
0039-2499(200108)32:8<1725:RDITIO>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
NON-HISPANIC WHITES; MEXICAN-AMERICANS; CARDIOVASCULAR-DISEASE; PHYSICAL-ACTIVITY; UNITED-STATES; MORTALITY; HYPERTENSION; BLACKS; PREVALENCE; ADULTS;
Keywords:
data interpretation, statistical; epidemiology; risk factors; stroke;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Sacco, RL Neurol Inst, 710 W 168Th St, New York, NY 10032 USA Neurol Inst 710 W 168Th St New York NY USA 10032 k, NY 10032 USA
Citazione:
R.L. Sacco et al., "Race-ethnic disparities in the impact of stroke risk factors - The Northern Manhattan Stroke Study", STROKE, 32(8), 2001, pp. 1725-1731

Abstract

Background and Purpose-Stroke risk factors have been determined in large part through epidemiological studies in white cohorts; as a result, race-ethnic disparities in stroke incidence and mortality rates remained unexplained. The aim in the present study was to compare the prevalence, OR, and etiological fraction (EF) of stroke risk factors among white, blacks, and Caribbean Hispanics living in the same urban community of northern Manhattan. Methods-In this population-based incident case-control study, cases (n=688) of first ischemic stroke were prospectively matched 1:2 by age, sex, and race-ethnicity with community controls (n=1156). Risk factors were determined through in-person assessment. Conditional logistic regression was used to calculate adjusted ORs in each race-ethnic group. Prevalence and multivariate EFs were determined in each race-ethnic group. Results-Hypertension was an independent risk factor for whites (OR 1.8, EF25%), blacks (OR 2.0, EF 37%), and Caribbean Hispanics (OR 2.1, EF 32%), but greater prevalence led to elevated EFs among blacks and Caribbean Hispanics. Greater prevalence rates of diabetes increased stroke risk in blacks (OR 1.8, EF 14%) and Caribbean Hispanics (OR 2.1 P <0.05, EF 10%) compared with whites (OR 1.0, EF 0%), whereas atrial fibrillation had a greater prevalence and EF for whites (OR 4.4, EF 20%) compared with blacks (OR 1.7, EF 3%) and Caribbean Hispanics (OR 3.0, EF 2%). Coronary artery disease was most important for whites (OR 1.3, EF 16%), followed by Caribbean Hispanics (OR 1.5, EF 6%) and then blacks (OR 1. 1, EF 2%). Prevalence of physical inactivity was greater in Caribbean Hispanics, but an elevated EF was found in all groups. Conclusions-The prevalence, OR, and EF for stroke risk factors vary by race-ethnicity. These differences are crucial to the etiology of stroke, as well as to the design and implementation of stroke prevention programs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 11:59:15