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Titolo:
Dengue fever - A review
Autore:
Strobel, M; Lamaury, I;
Indirizzi:
CHU Pointe A Pitre, Serv Malad Infect, F-97159 Pointe A Pitre, Guadeloupe,France CHU Pointe A Pitre Pointe A Pitre Guadeloupe France F-97159 eloupe,France
Titolo Testata:
REVUE DE MEDECINE INTERNE
fascicolo: 7, volume: 22, anno: 2001,
pagine: 638 - 647
SICI:
0248-8663(200107)22:7<638:DF-AR>2.0.ZU;2-R
Fonte:
ISI
Lingua:
FRE
Soggetto:
HEMORRHAGIC-FEVER; FRENCH-POLYNESIA; DISEASE SEVERITY; SHOCK SYNDROME; VIRUS; EPIDEMIC; MANIFESTATIONS; INFECTIONS; CORRELATE; VACCINES;
Keywords:
dengue fever; history; epidemiology;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Strobel, M CHU Pointe A Pitre, Serv Malad Infect, BP 465, F-97159 Pointe APitre, Guadeloupe, France CHU Pointe A Pitre BP 465 Pointe A Pitre Guadeloupe France F-97159
Citazione:
M. Strobel e I. Lamaury, "Dengue fever - A review", REV MED IN, 22(7), 2001, pp. 638-647

Abstract

Introduction. - Transmitted by Aedes mosquitoes all over the inter-tropical area, Dengue fever is the leading arboviral disease in humans. It is alsoan emerging disease. Current knowledge and key points. - Increasing morbidity-mortality, and geographical expansion are the drastic changes noted in the recent epidemiology of the disease. They are related to those occurring at the bio-climatic,socio-demographic and behavioural levels, which in turn may have led to enhanced viral circulation and virulence, and also vectorial resistance. The various clinical patterns (undifferentiated febrile episode of children, acute and algid classic form, the potentially fatal dengue hemorrhagic fever/dengue shock syndrome, and the atypical forms) are reviewed, as well as thediagnostic methods, and the pathogenesis (sequential infections, facilitating antibodies, capillary leakage). Future prospects and projects. - Dengue fever is actually much more than atravellers fever or an exotic curiosity. It presently threatens half the world's population, and remains a puzzling disease in many aspects, such as the virus-vector and host-virus relationships, and clinical expression variability. In this respect, dengue fever appears as a model of viral disease. The current molecular approach is expected to provide us with new insightsinto pathophysiology, more efficient tools for disease control, and also an efficient vaccine in the near future. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/08/20 alle ore 23:17:24