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Titolo:
Improving adherence to antidepressant drug treatment in primary care: a feasibility study for a randomized controlled trial of educational intervention
Autore:
Atherton-Naji, A; Hamilton, R; Riddle, W; Naji, S;
Indirizzi:
Univ Aberdeen, Hlth Serv Res Unit, Aberdeen AB25 2ZD, Scotland Univ Aberdeen Aberdeen Scotland AB25 2ZD it, Aberdeen AB25 2ZD, Scotland Royal Cornhill Hosp, Aberdeen, Scotland Royal Cornhill Hosp Aberdeen Scotland Cornhill Hosp, Aberdeen, Scotland Herdmanflat Hosp, Haddington, East Lothian, Scotland Herdmanflat Hosp Haddington East Lothian Scotland East Lothian, Scotland
Titolo Testata:
PRIMARY CARE PSYCHIATRY
fascicolo: 2, volume: 7, anno: 2001,
pagine: 61 - 67
SICI:
1355-2570(200106)7:2<61:IATADT>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENERAL-PRACTICE; CLINICAL-TRIALS; PATIENT EDUCATION; DEPRESSION; INFORMATION; MEDICATION; PHYSICIAN; OUTCOMES; THERAPY;
Keywords:
adherence; antidepressants; HADS; primary care;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Naji, S Univ Aberdeen, Hlth Serv Res Unit, Polwarth Bldg, Aberdeen AB25 2ZD, Scotland Univ Aberdeen Polwarth Bldg Aberdeen Scotland AB25 2ZD , Scotland
Citazione:
A. Atherton-Naji et al., "Improving adherence to antidepressant drug treatment in primary care: a feasibility study for a randomized controlled trial of educational intervention", PRIM CARE P, 7(2), 2001, pp. 61-67

Abstract

Poor adherence to prescribed medication is a well-documented waste of resources and may be particularly prevalent in depressive illness. Studies in primary care have suggested rates of non-adherence to antidepressants of 50-70%. We undertook a feasibility study of a randomized controlled trial of anovel intervention. Patents prescribed antidepressants in primary care were randomly allocated to receive a computer-generated educational intervention or to routine practice. Patients in the intervention groups received simple tailored information 1, 6 and 16 weeks after the initial prescription, which was personalized for each patient and specific drug and generated by a specially constructed computer programme. Comparisons were made in terms of collection of prescriptions over 6 months, mental health status (the Hospital Anxiety and Depression Scale (HADS)), frequencies of consultation, referrals and admissions and satisfaction with treatment. The five participating practices referred 61 patents to the study over 12 months, 45 of whom entered and completed the study. There were no statistically significant differences between the groups in the proportions of patients who collected prescriptions over 6 months, with the overall rates declining from 91% in month 1 to 56% in month 6. Patients in the intervention group had significantly lower HADS scores at 6 months. There were no significant differences in the numbers of consultations, referrals and admissions. Thus, whilst there were indications that the intervention might yield benefits for patients, the study was of insufficient statistical power to yield unequivocal results. The difficulties of recruiting patients in primary care are discussed and options for further research considered.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 12:52:34