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Titolo:
Enhanced corticosterone release after a modified forced swim test in Fawn hooded rats is independent of rearing experience
Autore:
Hall, FS; Sundstrom, JM; Lerner, J; Perth, A;
Indirizzi:
NIAAA, Clin Studies Lab, Bethesda, MD 20892 USA NIAAA Bethesda MD USA 20892 AAA, Clin Studies Lab, Bethesda, MD 20892 USA NIMH, Biol Psychiat Branch, Bethesda, MD 20892 USA NIMH Bethesda MD USA 20892 , Biol Psychiat Branch, Bethesda, MD 20892 USA Univ Maryland, Dept Psychol, College Pk, MD 20742 USA Univ Maryland College Pk MD USA 20742 t Psychol, College Pk, MD 20742 USA
Titolo Testata:
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
fascicolo: 3-4, volume: 69, anno: 2001,
pagine: 629 - 634
SICI:
0091-3057(200107/08)69:3-4<629:ECRAAM>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
WISTAR RATS; SOCIAL DEPRIVATION; ANIMAL-MODEL; RESPONSES; ETHANOL; ACCUMULATION; HIPPOCAMPUS; IMMOBILITY; DEPRESSION; PREFERENCE;
Keywords:
isolation rearing; forced swim test; Fawn hooded rats; stress; corticosterone; anxiety;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Hall, FS NIDA, IRP, Mol Neurobiol Branch, POB 5180,5500 Nathan Shock Dr, Baltimore,MD 21224 USA NIDA POB 5180,5500 Nathan Shock Dr Baltimore MD USA 21224 224 USA
Citazione:
F.S. Hall et al., "Enhanced corticosterone release after a modified forced swim test in Fawn hooded rats is independent of rearing experience", PHARM BIO B, 69(3-4), 2001, pp. 629-634

Abstract

Recent findings have demonstrated that Fawn hooded (FH/Har) rats exhibit enhanced plasma corticosterone (CORT) responses compared to Wistar rats after exposure to an open field, whereas this effect was not influenced by early social experience. In contrast, it was found that behavior in a modified version of the Porsolt Forced Swim Test (Porsolt FST) was affected by both strain and social experience. An important part of this study included modifications of the Porsolt FST that allowed separation of multiple behavioralendpoints. The present experiment was conducted to determine if FH/Har rats also exhibit enhanced CORT responses after exposure to the modified forced swim test, and whether CORT levels might predict the behavioral response in this context. After the initial exposure in the modified forced swim test FH/Har rats had higher CORT levels than Wistar rats, but this difference was not affected by isolation rearing. However, CORT levels were not correlated with the main behavioral measures assayed in this test. Nonetheless, the data confirm that FH/Har rats have altered HPA axis responses to stressors. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 18:51:25